Tag Archives: Pippin Prep

Impaired human immunodeficiency virus type 1 replicative fitness in atypical viremic non-progressor individuals

March 2017 Authors: Jan Weber, Richard Gibson, Lenka Sácká, Dmytro Strunin, et al. Info: In this publication, scientists describe an analysis of the rates of HIV progression in several patients. They determined that reduced viral replicative fitness appears to be … more »

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Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

March 2017 Authors: Warren Cheung, Xiaojian Shao, Andréanne Morin, Valérie Siroux, et al. Info: Researchers at McGill University and collaborating institutions used ChIP-seq to elucidate the effects of epigenetics and phenotype across the human genome. They analyzed more than 900 … more »

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Small genomic insertions form enhancers that misregulate oncogenes

February 2017 Authors: Brian J. Abraham, Denes Hnisz, Abraham S. Weintraub, Nicholas Kwiatkowski, et al. Info: In this paper, scientists report using ChIP-seq to better understand the role of non-coding somatic insertions in tumorigenesis. They identified enhancer-associated small insertions, often … more »

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Minimum sample sizes for population genomics: an empirical study from an Amazonian plant species

February 2017 Authors: Alison G. Nazareno, Jordan B. Bemmels, Christopher W. Dick, Lúcia G. Lohmann Info: Scientists in Michigan and São Paulo, Brazil, performed ddRAD-seq on two separate populations of Amphirrhox longifolia to determine how many SNPs and organisms have … more »

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Genetic diversity of Atlantic Bluefin tuna in the Mediterranean Sea: insights from genome-wide SNPs and microsatellites

February 2017 Authors: Aglaia Antoniou, Panagiotis Kasapidis, Georgios Kotoulas, Constantinos C. Mylonas and Antonios Magoulas Info: Scientists from the Hellenic Centre for Marine Research used ddRAD-seq to analyze genome-wide SNPs in the Atlantic Bluefin tuna, with the goal of understanding … more »

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Co-chaperone Hsp70/Hsp90 organizing protein (Hop) is Required for Transposon Silencing and piRNA Biogenesis

February 2017 Authors: Joseph A. Karam, Rasesh Y. Parikh, Dhananjaya Nayak, David Rosenkranz and Vamsi K. Gangaraju Info: Scientists from South Carolina and Mainz, Germany, studied Hop, a co-chaperone that interacts with a piRNA in Drosophila. They found that knocking … more »

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Metagenomic survey of the taxonomic and functional microbial communities of seawater and sea ice from the Canadian Arctic

February 2017 Authors: Etienne Yergeau, Christine Michel, Julien Tremblay, Andrea Niemi, Thomas L. King, Joanne Wyglinski, Kenneth Lee, and Charles W. Greera Info: Scientists from Canada and Australia studied how climate change may be affecting microbial communities by performing metagenomic … more »

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Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue

January 2017 Authors: Suriyan Ponnusamy, Quynh T. Tran, Innocence Harvey, Heather S. Smallwood, et al. Info: Scientists in Memphis, Tenn., studied obesity in mice, finding that estrogen receptor β and its ligands had a strong anti-obesity effect, reducing weight gain … more »

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Genomics-Based Marker Discovery and Diagnostic Assay Development for Wheat Blast

January 2017 Authors: Michael L. Pieck, Amy Ruck, Mark L. Farman, Gary L. Peterson, James P. Stack, Barbara Valent, and Kerry F. Pedley Info: Plant researchers published this look at Magnaporthe oryzae Triticum pathotype, the pathogen responsible for wheat blast … more »

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Comprehensive evaluation of extracellular small RNA isolation methods from serum in high throughput sequencing

January 2017 Authors: Yan Guo, Kasey Vickers, Yanhua Xiong, Shilin Zhao, Quanhu Sheng, Pan Zhang, Wanding Zhou and Charles R. Flynn Info: Scientists from Vanderbilt University and Van Andel Research Institute compared methods for isolating circulating extracellular small non-coding RNAs. … more »

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