Tag Archives: Pippin Prep

Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity

Posted on July 25, 2017 by Alex

July 2017 Authors: Kelley Yan, Olivier Gevaert, Grace Zheng, Benedict Anchang, et al. Info: In this project from scientists at Stanford University School of Medicine and other institutions, comparative RNA-seq was used to analyze putative mouse intestinal stem cells. The … more »

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Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice

Posted on July 25, 2017 by Alex

July 2017 Authors: Justin Quiles, Madhusudhanan Narasimhan, Gobinath Shanmugam, Brett Milash, John Hoidal, and Namakkal Rajasekaran Info: Scientists from the University of Alabama at Birmingham and other institutions studied a gene previously associated with oxidative stress, analyzing differential expression in … more »

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ddRAD-seq Study Explores Behavioral Roles in Speciation

Posted on July 25, 2017 by Alex

A new preprint from the Hoekstra lab at Harvard makes great use of the double digest RAD-seq protocol to better understand reproductive barriers and speciation in closely related species of mice. Since it was the Hoekstra lab that gave us … more »

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quaddRAD: a new high-multiplexing and PCR duplicate removal ddRAD protocol produces novel evolutionary insights in a nonradiating cichlid lineage

Posted on May 25, 2017 by Alex

May 2017 Authors: Franchini P, Monné Parera D, Kautt AF, Meyer A Info: Scientists from the University of Konstanz modified the original ddRAD-seq protocol to make it faster, more cost-effective, and higher-capacity. They report results from validating the new method … more »

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Impaired human immunodeficiency virus type 1 replicative fitness in atypical viremic non-progressor individuals

Posted on April 26, 2017 by Alex

March 2017 Authors: Jan Weber, Richard Gibson, Lenka Sácká, Dmytro Strunin, et al. Info: In this publication, scientists describe an analysis of the rates of HIV progression in several patients. They determined that reduced viral replicative fitness appears to be … more »

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Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

Posted on April 25, 2017 by Alex

March 2017 Authors: Warren Cheung, Xiaojian Shao, Andréanne Morin, Valérie Siroux, et al. Info: Researchers at McGill University and collaborating institutions used ChIP-seq to elucidate the effects of epigenetics and phenotype across the human genome. They analyzed more than 900 … more »

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Small genomic insertions form enhancers that misregulate oncogenes

Posted on March 25, 2017 by Alex

February 2017 Authors: Brian J. Abraham, Denes Hnisz, Abraham S. Weintraub, Nicholas Kwiatkowski, et al. Info: In this paper, scientists report using ChIP-seq to better understand the role of non-coding somatic insertions in tumorigenesis. They identified enhancer-associated small insertions, often … more »

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Minimum sample sizes for population genomics: an empirical study from an Amazonian plant species

Posted on March 25, 2017 by Alex

February 2017 Authors: Alison G. Nazareno, Jordan B. Bemmels, Christopher W. Dick, Lúcia G. Lohmann Info: Scientists in Michigan and São Paulo, Brazil, performed ddRAD-seq on two separate populations of Amphirrhox longifolia to determine how many SNPs and organisms have … more »

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Genetic diversity of Atlantic Bluefin tuna in the Mediterranean Sea: insights from genome-wide SNPs and microsatellites

Posted on March 25, 2017 by Alex

February 2017 Authors: Aglaia Antoniou, Panagiotis Kasapidis, Georgios Kotoulas, Constantinos C. Mylonas and Antonios Magoulas Info: Scientists from the Hellenic Centre for Marine Research used ddRAD-seq to analyze genome-wide SNPs in the Atlantic Bluefin tuna, with the goal of understanding … more »

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Co-chaperone Hsp70/Hsp90 organizing protein (Hop) is Required for Transposon Silencing and piRNA Biogenesis

Posted on March 25, 2017 by Alex

February 2017 Authors: Joseph A. Karam, Rasesh Y. Parikh, Dhananjaya Nayak, David Rosenkranz and Vamsi K. Gangaraju Info: Scientists from South Carolina and Mainz, Germany, studied Hop, a co-chaperone that interacts with a piRNA in Drosophila. They found that knocking … more »

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