Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice

July 2017

Justin Quiles, Madhusudhanan Narasimhan, Gobinath Shanmugam, Brett Milash, John Hoidal, and Namakkal Rajasekaran

Scientists from the University of Alabama at Birmingham and other institutions studied a gene previously associated with oxidative stress, analyzing differential expression in knockout and wild type mouse hearts. They found that the gene may regulate cardiac microRNAs. The team used Pippin Prep to size libraries before sequencing on an Illumina HiSeq.

BMC Genomics 2017 18:509
DOI: 10.1186/s12864-017-3875-3

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