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Recent Posts
- Targeted Phasing of 2-200 Kilobase DNA Fragments with a Short-Read Sequencer and a Single-Tube Linked-Read Library Method
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- Utility of long-read sequencing for All of Us
- Significance of HLA in the development of Graves’ orbitopathy
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Category Archives: Blog
AGBT23 Roundup!
Well, we have another fabulous AGBT behind us that we were happy to attend. Our take home messages? A. Spatial transcriptomics is the exciting new frontier. B. True human WGS has been accomplished and is moving into population-scale work. And … more »
HLS-CATCH and TELL-Seq: Haplotype Phasing of a 187kb HMW Gene Targets from a Trio
We here at Sage Science are excited to have joined forces with Universal Sequencing Technology to promote their TELL-Seq barcode linked-read technology. One of the reasons for our excitement is that TELL-Seq, and the transposase-based barcoding method benefits greatly from … more »
Unleash Your Illumina Sequencer with TELL-Seq™ Linked Reads
We’re proud to announce today that we will be selling TELL-Seq™ linked library prep kits from Universal Sequencing Technology. TELL-Seq, Transposase Enzyme Linked Long-read Sequencing, is a scalable NGS library technology with a very simple workflow that can provide you … more »
Posted in Applications, Blog
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HLS-CATCH and TELL-Seq™: a new route to Targeted Long-Fragment Linked-Read Sequencing
At the recent 2020 AGBT meeting Universal Sequencing gave a data-filled poster on their new Transposase Enzyme Linked Long-read Sequencing kit and workflow, known as TELL-Seq™. The technology features a unique combination of bead-linked and soluble transposases that can generate … more »
Posted in Blog
Tagged HLS-CATCH, linked-read, SageHLS, TELL-Seq
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SageHLS Helps Unravel the Neuropsychiatric 22q11.2 Deletion Region1q11
An international collaboration led by the Stanford labs of Alexander Urban and Hanlee Ji, used the SageHLS system to map a Mb-sized deletion in a complex region of the human genome, 22q11.2, that is associated with a variety of neurodevelopmental … more »
SageHLS sample prep for ultra-long Nanopore Sequencing at NextOmics/GrandOmics
NextOmics/GrandOmics is the largest third-generation sequencing service company in China. The NextOmics division focuses on animal, plant and bacterial genome sequencing, while GrandOmics focuses on human genome sequencing. GrandOmics became the first certified PromethIon service provider in China in June, … more »
Posted in Uncategorized
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AGBT 2019 Re-Cap
AGBT 2019 was a smashing success this year. Featuring a triumphant return to Marco Island FL with postcard perfect weather, the science was (as usual) top-notch. The renovated Marriott greatly upgraded its conference facilities and added an attractive new tower … more »
Posted in Blog
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Linked-Read Sequencing Advances Understanding of Cancers
A new study* from the University of Connecticut Medical School, Jackson Labs, and collaborators demonstrate the utility of using emulsion based linked-read sequencing (10X Genomics) for cancer research. Published in January’s Otology & Neurotology studies patients with Neurofibromatosis Type 2 … more »
Posted in Blog
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SageELF Size Selection for PacBio Circular Consensus Sequencing
A new preprint has landed on BioRxiv that reports on high-accuracy circular consensus sequencing (CCS) on the PacBio Sequel. The study, “Highly-accurate long-read sequencing improves variant detection and assembly of a human genome”, is authored by PacBio and an impressive … more »
Posted in Blog
Tagged long-read sequencing, PacBio, SageELF
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Product Update: The High Pass Plus Cassette
The High Pass Plus™ gel cassette is the newest addition to the Pippin Family. As the name suggests, it is dedicated to our BluePippin “High-Pass” DNA size selection which has been a go-to method for increasing the read lengths for … more »
Posted in Blog
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