Monthly Archives: May 2014

SFAF 2014: Do You Know the Way to Santa Fe?

It seems we just can’t get enough of genomics conferences! This week, Sage Science is proud to be a sponsor of the Sequencing, Finishing, and Analysis in the Future conference hosted by Los Alamos National Laboratory (May 28-30). We’ll be … more »

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Discovery of transgene insertion sites by high throughput sequencing of mate pair libraries

May 2014 Authors: Anuj Srivastava, Vivek M Philip, Ian Greenstein, Lucy B Rowe, Mary Barter, Cathleen Lutz and Laura G Reinholdt Info: Jackson Laboratory scientists developed a method to characterize and score transgene insertion sites in mice to help researchers … more »

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Microbes in the Spotlight: ASM 2014

Earlier this week, thousands of microbiologists descended on Boston for the annual meeting of the American Society for Microbiology. The Sage Science team was thrilled to be part of the festivities. Many thanks to all of the scientists who visited … more »

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SimRAD: a R package for simulation-based prediction of the number of loci expected in RADseq and similar genotyping by sequencing approaches

May 2014 (epub ahead of print) Authors: Olivier Lepais and Jason T Weir Info: This article from Molecular Ecology Resources describes a new software tool designed to help scientists optimize their double-digest RADseq (ddRADseq) experiments by accurately estimating the number … more »

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Pippin Enriches for MicroRNAs in Zebrafish Transcriptome Study

Scientists from the Mayo Clinic, Institute for Systems Biology, and University of Illinois recently published a study investigating the effects of vitamin D on microRNA regulation of gene expression in zebrafish. The team used our Pippin Prep together with the … more »

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Genome Editing Shows Potential for Shrinking Repeat Expansions

Several diseases, many of them involving neurological symptoms, have been linked to expansions of trinucleotide repeat sequences. These repeat expansion disorders include Fragile X syndrome, Huntington’s disease, and various forms of epilepsy and ataxia. In Fragile X, for example, a … more »

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Quality control of next-generation sequencing data without a reference

May 2014 Authors: Urmi H Trivedi, Timothée Cézard, Stephen Bridgett, Anna Montazam, Jenna Nichols, Mark Blaxter, and Karim Gharbi Info: In this paper published in Frontiers in Genetics, scientists at the University of Edinburgh show that it is possible to … more »

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