Monthly Archives: May 2013

New Prostate Cancer Research Indicates Rapid Accumulation of DNA Mutations

Researchers studying the behavior of prostate cancer have shed light on how the cancer develops mutations so rapidly. In contrast to other cancers that seem to progress by adding mutations one at a time, the prostate cancer samples that were … more »

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Deciphering the Growth Behaviour of Mycobacterium africanum

May 2013 Authors: Florian Gehre, Jacob Otu, Kathryn DeRiemer, Paola Florez de Sessions, Martin L. Hibberd, Wim Mulders, Tumani Corrah, Bouke C. de Jong, Martin Antonio Info: The Pippin Prep was used to size select libraries prepared with the New … more »

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Multiplex target capture with double-stranded DNA probes

May 2013 Authors: Peidong Shen, Wenyi Wang, Aung-Kyaw Chi, Yu Fan, Ronald W Davis, Curt Scharfe Info: The authors describe a new method for targeted NGS using double-stranded probes rather than single-stranded ones, improving sensitivity for variant detection, and at … more »

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Pacific Biosciences and Sage Science Announce Co-Marketing Partnership

MENLO PARK, Calif. and BEVERLY, Mass. — May 16, 2013 — Pacific Biosciences of California, Inc., (NASDAQ:PACB), provider of the PacBio® RS II DNA Sequencing System, and Sage Science, a developer of life science products for improving sample preparation processes … more »

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Pippin and PacBio: Better Together

Update: Just announced– Sage Science and Pacific Biosciences have partnered to offer users longer reads than ever. Click here to read the press release. The new SMRTbellTM 20kb sample prep protocol using the BluePippin is posted on the PacBio® SampleNet … more »

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RESTseq – Efficient Benchtop Population Genomics with RESTriction Fragment SEQuencing

May 2013 Authors: Eckart Stolle1, Robin F. A. Moritz Info: The authors present a new method for SNP analysis in population genomics. The Pippin Prep was used to size select DNA for the Ion Torrent PGM platform . Citation: PLoS … more »

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FOXO1 regulates expression of a microRNA cluster on X chromosome

May 2013 Authors: Ruchi Singhal, Jonathan E. Bard, Norma J. Nowak, Michael J.Buck, and Eugene S. Kandel Info: The Pippin Prep was used in size selection with the Illumina TruSeq Small RNA sequencing protocol. Citation: AGING 5(5): 347-356 http://www.impactaging.com/papers/v5/n5/full/100558.html

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Pippin Pulse

Field Inversion Gel Electrophoresis       We’ve set up this post to provide Pippin Pulse users with a resource to keep updated on new protocols and to post references that might be useful. We also invite users to feel … more »

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