Sage Science is pleased to introduce the MegaPulse™ (MGP0200), a new pulsed-field electrophoresis power supply that supports both Field-Inversion Gel Electrophoresis (FIGE) and Zero-Integrated-Field Electrophoresis (ZIFE) while running one or two standard agarose midi gel boxes simultaneously. In a typical FIGE workflow, DNA fragments above ~450 kb compress into an unresolved band. ZIFE overcomes this by simultaneously switching the field magnitude, direction, and pulse time so that the net time-integrated field approaches zero — extending practical resolution to 1.6 Mb. Seven pre-validated protocols cover 0.5 kb to 1.6 Mb across both modes, and an Advanced Programming interface allows custom waveforms to be built and saved. The MegaPulse is well-suited for HMW genomic DNA QC ahead of long-read sequencing library prep.
