Monthly Archives: February 2017

Complete genome sequence of Lutibacter profundi LP1Tisolated from an Arctic deep-sea hydrothermal vent system

January 2017 Authors: Juliane Wissuwa, Sven Le Moine Bauer, Ida Helene Steen, and Runar Stokke Info: Scientists from the University of Bergen used PacBio sequencing to produce a complete genome assembly for Lutibacter profundi LP1T, an extremophile isolated from a … more »

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Antibiotic discovery throughout the Small World Initiative: A molecular strategy to identify biosynthetic gene clusters involved in antagonistic activity

January 2017 Authors: Elizabeth Davis, Tyler Sloan, Krista Aurelius, Angela Barbour, et al. Info: Through a citizen science program, college students analyzed 77 soil-derived bacteria to promote genetic characterization and antibiotic discovery for the fight against drug-resistant pathogens. They chose … more »

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Genomic and transcriptomic resources for assassin flies including the complete genome sequence of Proctacanthus coquilletti (Insecta: Diptera: Asilidae) and 16 representative transcriptomes

January 2017 Authors: Rebecca B. Dikow, Paul B. Frandsen, Mauren Turcatel, and Torsten Dikow Info: Researchers at the Smithsonian Institution published a high-quality draft genome, 16 transcriptomes, and a time-calibrated phylogeny for the assassin fly. They also include bioinformatics tools … more »

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Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue

January 2017 Authors: Suriyan Ponnusamy, Quynh T. Tran, Innocence Harvey, Heather S. Smallwood, et al. Info: Scientists in Memphis, Tenn., studied obesity in mice, finding that estrogen receptor β and its ligands had a strong anti-obesity effect, reducing weight gain … more »

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Genomics-Based Marker Discovery and Diagnostic Assay Development for Wheat Blast

January 2017 Authors: Michael L. Pieck, Amy Ruck, Mark L. Farman, Gary L. Peterson, James P. Stack, Barbara Valent, and Kerry F. Pedley Info: Plant researchers published this look at Magnaporthe oryzae Triticum pathotype, the pathogen responsible for wheat blast … more »

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Comprehensive evaluation of extracellular small RNA isolation methods from serum in high throughput sequencing

January 2017 Authors: Yan Guo, Kasey Vickers, Yanhua Xiong, Shilin Zhao, Quanhu Sheng, Pan Zhang, Wanding Zhou and Charles R. Flynn Info: Scientists from Vanderbilt University and Van Andel Research Institute compared methods for isolating circulating extracellular small non-coding RNAs. … more »

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Whole Genome Amplification and Reduced-Representation Genome Sequencing of Schistosoma japonicum Miracidia

January 2017 Authors: Jonathan A. Shortt, Daren C. Card, Drew R. Schield, Yang Liu, Bo Zhong, Todd A. Castoe, Elizabeth J. Carlton, and David D. Pollock Info: Researchers used ddRAD-seq to study the schistosome species S. japonicum miracidia, finding that … more »

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MicroRNA biomarkers of pancreatic injury in a canine model

January 2017 Authors: Rodney Rouse, Barry Rosenzweig, Katie Shea, Alan Knapton, Sharron Stewart, Lin Xu, Ashok Chockalingam, Leah Zadrozny, and Karol Thompson Info: FDA scientists report results of studying five pancreas-enriched microRNAs as potential biomarkers for pancreatic injury. They used … more »

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The Darling of AGBT: HMW DNA

The Sage Science team had a blast at this year’s AGBT conference in Hollywood, Fla. We thoroughly enjoyed the parties, the beach, and especially the excellent talks. We’d like to thank all of the attendees who made their way to … more »

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Sage Science Launches Instrument to Purify High-Quality DNA Directly from Cells

BEVERLY, Mass. — February 13, 2017 — Sage Science, a developer of products for improving sample preparation processes in life science applications, today announced the launch of a new platform that can extract and purify extremely large DNA fragments directly … more »

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