Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

March 2017

Warren Cheung, Xiaojian Shao, Andréanne Morin, Valérie Siroux, et al.

Researchers at McGill University and collaborating institutions used ChIP-seq to elucidate the effects of epigenetics and phenotype across the human genome. They analyzed more than 900 samples to understand the effects of epigenetic regulation. The team used Pippin Prep to size-select fragments prior to sequencing on an Illumina HiSeq 2000.

Genome Biology (2017) 18:50
DOI 10.1186/s13059-017-1173-7

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