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Monthly Archives: May 2016
For PacBio’s Iso-Seq Method, Users Deploy SageELF or BluePippin Size Selection
More and more scientists are using their PacBio systems for transcriptome studies, generating full-length isoforms with the Iso-Seq method. The number of novel transcripts discovered and the implications for alternative splicing are a not-so-subtle reminder that we still have a … more »
How to Work with Large DNA: Data from the Sage HLS Platform
The Sage Science R&D team has been hard at work on our newest tool, to be released later this year. The HLS platform, which we first described at the Festival of Genomics meeting in Boston last year, is our answer … more »
Urban Mice: NYC Study Sheds Light on Population Diversity and Changes
They may make subway riders shudder, but New York City mice are the stars of a cool new paper outlining their evolutionary history during a rapid period of urbanization. Scientists from the City University of New York used ddRAD-seq to … more »
Posted in Blog
Tagged ddRADseq, genotyping, HiSeq, Illumina, Pippin Prep
Comments Off on Urban Mice: NYC Study Sheds Light on Population Diversity and Changes
Spotted in the Literature: The First PippinHT Publication!
We began shipping the high-throughput version of our automated Pippin DNA size selection platform last year, and it’s a thrill to see what we believe is the first reference to it in a peer-reviewed publication. A team of scientists from … more »
Multi-omics maps of cotton fibre reveal epigenetic basis for staged single-cell differentiation
April 2016 Authors: Maojun Wang, Pengcheng Wang, Lili Tu, Sitao Zhu, Lin Zhang, Zhonghua Li, Qinghua Zhang, Daojun Yuan, and Xianlong Zhang Info: Scientists from Huazhong Agricultural University in China studied the epigenetics of single-cell differentiation in cotton, finding clear … more »
Building on a RAD Idea
It’s been a few years since the Hoekstra lab at Harvard first published its double-digest RAD-seq protocol. Since then, the approach has been rapidly adopted by the community for massively parallel genotyping, particularly of non-model organisms, and has been the … more »
Urbanization shapes the demographic history of a native rodent (the white-footed mouse, Peromyscus leucopus) in New York City
April 2016 Authors: Stephen E. Harris, Alexander T. Xue, Diego Alvarado-Serrano, Joel T. Boehm, Tyler Joseph, Michael J. Hickerson, Jason Munshi-South Info: Researchers at the City University of New York studied populations of white-footed mice in New York City and … more »
Posted in Citation
Tagged ddRADseq, Pippin Prep
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Patterns of genome-wide variation in Glossina fuscipes fuscipes tsetse flies from Uganda
April 2016 Authors: Gloria-Soria A, Dunn WA, Telleria EL, Evans BR, Okedi L, Echodu R, Warren WC, Montague MJ, Aksoy S, Caccone A Info: Researchers used ddRAD-seq to develop a panel of SNPs for use in population genomics or genome-wide … more »
Posted in Citation
Tagged BluePippin, ddRADseq
Comments Off on Patterns of genome-wide variation in Glossina fuscipes fuscipes tsetse flies from Uganda