Tag Archives: microRNA

Distinct Profiles of Cell-Free MicroRNAs in Plasma of Veterans with Post-Traumatic Stress Disorder

July 2019 Authors: Min Young Lee, David Baxter, Kelsey Scherler , Taek-Kyun Kim, Xiaogang Wu , Duna Abu-Amara, Janine Flory, Rachel Yehuda, Charles Marma, Marti Jett, Inyoul Lee, Kai Wang, and Leroy Hood Info: Researchers report on studies that profile … more »

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Comparison of RNA isolation and library preparation methods for small RNA sequencing of canine biofluids

Authors: Candice P. Chu, Mary B. Nabity Info: From the Department of Veterinary Pathobiology at Texas A&M, this study evaluates best practices for small RNA sequencing from canine biofluid samples (serum and urine). The study compares RNA-seq results after using … more »

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Identification of whole blood mRNA and microRNA biomarkers of tissue damage and immune function resulting from amphetamine exposure or heat stroke in adult male rats

February 2019 Authors: Luısa Camacho, Camila S. Silva, Joseph P. Hanig, Robert P. Schleimer, Nysia I. George, John F. Bowyer Info: A report from the USDA and others evaluate the effect of amphetamine and methamphetamine toxicity on immune systems and … more »

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Cancer stem cell–associated miRNAs serve as prognostic biomarkers in colorectal cancer

March 2019 Authors: Shusuke Toden, Shigeyasu Kunitoshi, Jacob Cardenas, Jinghua Gu, Elizabeth Hutchins, Kendall Van Keuren-Jensen, Hiroyuki Uetake, Yuji Toiyama, and Ajay Goel Info: This study evaluates cancer stems cells (CSC) which resist chemotherapy agents and have high tumor initiation … more »

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Transmission of microRNA antimiRs to mouse offspring via the maternal-placental-fetal unit

March 2018 Authors: Jonas Hönig, Ivana Mižíková, Claudio Nardiello, David Emanuel Surate Solaligue, et al. Info: In Germany, researchers delivered microRNA inhibitors to pregnant mice, finding that the antimiRs were then detectable in offspring, where they caused fewer off-target effects … more »

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Study protocol: rationale and design of the community-based prospective cohort study of kidney function and diabetes in rural New Mexico, the COMPASS study

February 2018 Authors: Antonin Jaros, Hafiz Sroya, Venita Wolfe, Vikas Ghai, et al. Info: Scientists report design and launch of the COMPASS study, a prospective, longitudinal cohort in rural New Mexico aimed at better understanding diabetic chronic kidney disease and … more »

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Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI

December 2017 Authors: Ruben Boers, Joachim Boers, Bas de Hoon, Christel Kockx, et al. Info: Scientists at Erasmus Medical Center determined that analysis of genome-wide methylation is challenging when fragment sizes are too small and that better epigenetic results are … more »

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Micro RNA’s (miRNA’s) may help explain expression of multiple genes in Alzheimer’s Frontal Cortex

September 2017 Authors: James Bennett and Paula Keeney Info: Scientists from Neurodegeneration Therapeutics used RNA-seq to compare microRNAs found in Alzheimer’s brain samples and controls. They identified 55 up-regulated genes and 191 down-regulated genes in the Alzheimer’s samples. PippinHT was … more »

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Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice

July 2017 Authors: Justin Quiles, Madhusudhanan Narasimhan, Gobinath Shanmugam, Brett Milash, John Hoidal, and Namakkal Rajasekaran Info: Scientists from the University of Alabama at Birmingham and other institutions studied a gene previously associated with oxidative stress, analyzing differential expression in … more »

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Co-chaperone Hsp70/Hsp90 organizing protein (Hop) is Required for Transposon Silencing and piRNA Biogenesis

February 2017 Authors: Joseph A. Karam, Rasesh Y. Parikh, Dhananjaya Nayak, David Rosenkranz and Vamsi K. Gangaraju Info: Scientists from South Carolina and Mainz, Germany, studied Hop, a co-chaperone that interacts with a piRNA in Drosophila. They found that knocking … more »

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