Tag Archives: Pippin Prep

Genetic Basis for the Biosynthesis of the Pharmaceutically Important Class of Epoxyketone Proteasome Inhibitors

October 2013 Authors: Michelle Schorn, Judith Zettler, Joseph P. Noel, Pieter C. Dorrestein, Bradley S. Moore, and Leonard Kaysser Info: Scientists from California and Germany teamed up to study genes that encode for the biosynthesis of an important component of … more »

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Quick, sensitive and specific detection and evaluation of quantification of minor variants by high-throughput sequencing

October 2013 Authors: Ross Ka-Kit Leung, Zhi Qiang Dong, Fei Sa, Cheong Meng Chong, Si Wan Lei,c Stephen Kwok-Wing Tsui and Simon Ming-Yuen Lee Info: Scientists from the University of Hong Kong and the University of Macau, China, evaluate errors … more »

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Genomic architecture of ecologically divergent body shape in a pair of sympatric crater lake cichlid fishes

October 2013 Authors: PAOLO FRANCHINI, CARMELO FRUCIANO, MARIA L. SPREITZER, JULIA C. JONES, KATHRYN R. ELMER, FREDERICO HENNING and AXEL MEYER Info: Researchers at the University of Konstanz, Germany, look at the speciation of chichlid fishes using the ddRAD technique. … more »

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Improved Protocols for Illumina Sequencing

October 2013 Authors: Iraad F. Bronner, Michael A. Quail, Daniel J. Turner, and Harold Swerdlow Info: A comprehensive overview of the state-of-the state of Illumina sequencing, from the Wellcome Trust Sanger Institute and Oxford Nanopore Technologies. The value of narrow … more »

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In Skin Microbiome Study, Scientists Find Host Genotype Influences Bacterial Populations

A paper that came out in the Journal of Innate Immunity this summer reports that a person’s genotype affects which microbes will colonize his or her skin, which in turn may alter that person’s defense mechanisms against pathogenic organisms. “Skin … more »

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De novo transcriptome assembly of drought tolerant CAM plants, Agave deserti and Agave tequilana

August 2013 Authors: Stephen M Gross, Jeffrey A Martin, June Simpson, María Jazmín Abraham-Juarez, Zhong Wang and Axel Visel Info: Agave is an interesting plant for bioenergy study. This paper provides transcriptome data of two strains. The Pippin Prep was … more »

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Comparative genomics of Campylobacter concisus isolates reveals genetic diversity and provides insights into disease association

August 2013 Authors: Nandan P Deshpande, Nadeem O Kaakoush, Marc R Wilkins and Hazel M Mitchell Info: Collaborators at the University of New South Wales sequence several strains of Campylobacter concisus from healthy and diseased (Crohn’s disease and gastroenteritis) individuals … more »

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A quantitative reference transcriptome for Nematostella vectensis early embryonic development: a pipeline for de novo assembly in emerging model systems

June 2013 Authors: Sarah Tulin, Derek Aguiar, Sorin Istrail, and Joel Smith Info: Scientists from the Marine Biological Laboratory and Brown University developed a new pipeline for de novo transcriptome assembly that can be used with organisms lacking a well-annotated … more »

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Phylogeographic Origin of Helicobacter pylori Determines Host-Adaptive Responses upon Coculture with Gastric Epithelial Cells

July 2013 Authors: Alexander Sheh, Rupesh Chaturvedi, D. Scott Merrell, Pelayo Correa, Keith T. Wilson, James G. Fox Info: A study of gene expression comparing several strains of H. pylori. The BluePippin was used to size-select fragments to construct paired-end … more »

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The new sequencer on the block: comparison of Life Technology’s Proton sequencer to an Illumina HiSeq for whole-exome sequencing

June 2013 Authors: Joseph F. Boland, Charles C. Chung, David Roberson, Jason Mitchell, Xijun Zhang, Kate M. Im, Ji He, Stephen J. Chanock, Meredith Yeager, Michael Dean Info: An exome-sequencing study from the NIH comparing Illumina/Nimblegen to Ion Torrent/TargetSeq. Pippin … more »

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