Quick, sensitive and specific detection and evaluation of quantification of minor variants by high-throughput sequencing

October 2013

Ross Ka-Kit Leung, Zhi Qiang Dong, Fei Sa, Cheong Meng Chong, Si Wan Lei,c Stephen Kwok-Wing Tsui and Simon Ming-Yuen Lee

Scientists from the University of Hong Kong and the University of Macau, China, evaluate errors in detecting minor variants and suggest rules for authenticating the variants and improving accuracy of detection. The Pippin Prep was used for library preparation on the Ion Torrent platform.

Mol. BioSyst., 2014, 10, 206


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