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Recent Posts
- New BluePippin 2.5% Agarose Cassettes Provide High Size Selection Accuracy Between 100-600bp
- Enriching for Answers in Rare Diseases
- Phased genome assemblies and pangenome graphs of human populations of Japan and Saudi Arabia
- New PippinHT Cassette: >10kB High-Pass with Internal Standards
- Genome-wide comparative analysis of variability and population structure between autochthonous Turkish chicken breeds and commercial hybrid lines
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Author Archives: Alex
Comprehensive evaluation of extracellular small RNA isolation methods from serum in high throughput sequencing
January 2017 Authors: Yan Guo, Kasey Vickers, Yanhua Xiong, Shilin Zhao, Quanhu Sheng, Pan Zhang, Wanding Zhou and Charles R. Flynn Info: Scientists from Vanderbilt University and Van Andel Research Institute compared methods for isolating circulating extracellular small non-coding RNAs. … more »
Posted in Citation
Tagged microRNA, miRNA, NextSeq, Pippin Prep
Comments Off on Comprehensive evaluation of extracellular small RNA isolation methods from serum in high throughput sequencing
Whole Genome Amplification and Reduced-Representation Genome Sequencing of Schistosoma japonicum Miracidia
January 2017 Authors: Jonathan A. Shortt, Daren C. Card, Drew R. Schield, Yang Liu, Bo Zhong, Todd A. Castoe, Elizabeth J. Carlton, and David D. Pollock Info: Researchers used ddRAD-seq to study the schistosome species S. japonicum miracidia, finding that … more »
Posted in Citation
Tagged ddRADseq, MiSeq, Pippin Prep
Comments Off on Whole Genome Amplification and Reduced-Representation Genome Sequencing of Schistosoma japonicum Miracidia
MicroRNA biomarkers of pancreatic injury in a canine model
January 2017 Authors: Rodney Rouse, Barry Rosenzweig, Katie Shea, Alan Knapton, Sharron Stewart, Lin Xu, Ashok Chockalingam, Leah Zadrozny, and Karol Thompson Info: FDA scientists report results of studying five pancreas-enriched microRNAs as potential biomarkers for pancreatic injury. They used … more »
The Darling of AGBT: HMW DNA
The Sage Science team had a blast at this year’s AGBT conference in Hollywood, Fla. We thoroughly enjoyed the parties, the beach, and especially the excellent talks. We’d like to thank all of the attendees who made their way to … more »
Sage Science Launches Instrument to Purify High-Quality DNA Directly from Cells
BEVERLY, Mass. — February 13, 2017 — Sage Science, a developer of products for improving sample preparation processes in life science applications, today announced the launch of a new platform that can extract and purify extremely large DNA fragments directly … more »
Posted in News, News, Press Release
Comments Off on Sage Science Launches Instrument to Purify High-Quality DNA Directly from Cells
Calling All Technophiles: Time for AGBT!
The Sage Science team is casting off the shackles of winter and gearing up for a trip to sunny Florida for the annual Advances in Genome Biology and Technology meeting. We look forward to this conference each year — it’s … more »
QseC inhibition as an antivirulence approach for colitis-associated bacteria
January 2017 Authors: Michelle G. Rooks, Patrick Veiga, Analise Z. Reeves, Sydney Lavoie, et al. Info: In this paper, scientists from Harvard and other institutions describe a study of quorum-sensing regulators in E. coli as a possible means of reducing … more »
Posted in Citation
Tagged MiSeq, Pippin Prep
Comments Off on QseC inhibition as an antivirulence approach for colitis-associated bacteria
Podcast: Structural Variation Pioneer Evan Eichler on Moving Toward the Clinic
We’ve been big fans of the structural variation work coming out of Evan Eichler’s University of Washington lab for years, so when he was the subject of a Mendelspod interview, we couldn’t wait to listen. If you missed the podcast, … more »
RAD-seq, High-Pass Sizing in Sunny San Diego
We are shaking off this northeast winter and heading out to San Diego for the 25th annual International Plant and Animal Genome meeting! This event is always a great way to kick off the year, surrounded by cutting-edge science and … more »
Targeted capture and sequencing of gene-sized DNA molecules
December 2016 Authors: Michael Giolai, Pirita Paajanen, Walter Verweij, Lawrence Percival-Alwyn, et al. Info: Scientists adapted the RenSeq capture method for long-read PacBio sequencing, optimizing the method through improved shearing, size selection, and PCR amplification. They used SageELF extensively to … more »