Tag Archives: Ion Torrent

Low-Coverage Sequencing No Challenge for Structural Variant Detection

Posted on July 21, 2016 by Alex

Is it really possible to detect somatic structural variants accurately from a single sequencing read? A new protocol from scientists at the Albert Einstein College of Medicine in New York and Voronezh State University in Russia was designed to do … more »

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Next generation sequencing to identify novel genetic variants causative of autosomal dominant familial hypercholesterolemia associated with increased risk of coronary heart disease

Posted on September 28, 2015 by Alex

July 2015 Authors: Faisal A. Al-Allaf, Mohammad Athar, Zainularifeen Abduljaleel, Mohiuddin M. Taher, Wajahatullah Khan, Faisal A. Ba-hammam, Hala Abalkhail, Abdullah Alashwal Info: Scientists from Saudi Arabia published a paper in Gene demonstrating the use of targeted sequencing to detect … more »

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Isolation via next-generation sequencing of microsatellites from the Tasmanian macroalgae Lessonia corrugata (Lessoniaceae)

Posted on September 28, 2015 by Alex

July 2015 Authors: Halley M. S. Durrant, Christopher P. Burridge, and Michael G. Gardner Info: Scientists from Australia developed microsatellite markers for this macroalgae, an important component of the local marine ecosystem, that will allow for future population genetic studies … more »

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Towards allele-level human leucocyte antigens genotyping – assessing two next-generation sequencing platforms: Ion Torrent Personal Genome Machine and Illumina MiSeq

Posted on July 2, 2015 by Alex

June 2015 Authors: J. L. Duke, C. Lind, K. Mackiewicz, D. Ferriola, A. Papazoglou, O. Derbeneva, D. Wallace, and D. S. Monos Info: This publication in the International Journal of Immunogenetics from scientists at the Children’s Hospital of Philadelphia presents … more »

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At Einstein Med School, ‘Extremely Reproducible’ Pippin Platforms Save Time and Money

Posted on May 19, 2015 by Alex

In the genetics department at Albert Einstein College of Medicine, Research Assistant Professor Alex Maslov is working to understand structural variants associated with aging and cancer. Using human and mouse cells, he deploys whole genome sequencing to make these links. … more »

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Double-digest RAD sequencing using Ion Proton semiconductor platform (ddRADseq-ion) with nonmodel organisms

Posted on May 13, 2015 by Alex

April 2015 Authors: Hans Recknagel, Arne Jacobs, Pawel Herzyk, Kathryn R Elmer Info: In this Molecular Ecology Resources paper, researchers from the University of Glasgow describe a protocol and adapters they developed for double-digest RAD sequencing on the Ion Torrent … more »

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Improved transposon-based library preparation for the Ion Torrent platform

Posted on April 21, 2015 by Alex

April 2015 Authors: Tatyana Gorbacheva, Wilber Quispe-Tintaya, Vasily N. Popov, Jan Vijg, and Alexander Y. Maslov Info: In this Biotechniques paper, scientists from the Albert Einstein College of Medicine in New York describe MuPlus, a new transposon-based method for barcoded … more »

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Evaluation of a Pyrenophora teres f. teres mapping population reveals multiple independent interactions with a region of barley chromosome 6H

Posted on October 2, 2014 by Alex

August 2014 Authors: Rachel A. Shjerve, Justin D. Faris, Robert S. Brueggeman, Changhui Yan, Ya Zhu, Vaidehi Koladia, Timothy L. Friesen Info: Researchers in North Dakota studied the genetics of virulence in a fungal pathogen that affects barley. They looked … more »

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Improved Multiple Displacement Amplification (iMDA) and Ultraclean Reagents

Posted on June 5, 2014 by Alex

June 2014 Authors: S Timothy Motley, John M Picuri, Chris D Crowder, Jeremiah J Minich, Steven A Hofstadler and Mark W Eshoo Info: In this methods paper, researchers from Ibis Biosciences report a superior whole-genome amplification protocol that can be … more »

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Comprehensive profiling of the vaginal microbiome in HIV positive women using massive parallel semiconductor sequencing

Posted on March 7, 2014 by Alex

March 2014 Authors: Adam Ameur, Tracy L. Meiring, Ignas Bunikis, Susana Ha¨ggqvist, Cecilia Lindau, Julia Hedlund Lindberg, Inger Gustavsson, Zizipho Z. A. Mbulawa, Anna-Lise Williamson and Ulf Gyllensten Info: Researchers at Uppsala University, Sweden, along with the University of Cape … more »

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