Tag Archives: Pippin Prep

Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics

Posted on April 13, 2015 by Alex

March 2015 Authors: Stephanie J Yaung, Luxue Deng, Ning Li, Jonathan L Braff, George M Church, Lynn Bry, Harris H Wang, Georg K Gerber Info: In this Molecular Systems Biology paper, researchers from Harvard and Columbia discuss the use of … more »

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New Structural Variant Analysis Method Uses Targeted Capture and Sequencing of Large-Insert DNA

Posted on April 7, 2015 by Alex

In a new BMC Genomics paper, scientists from Baylor College of Medicine describe a new method for accurate, affordable interrogation of structural variants across the human genome. We’re delighted to see that automated DNA size selection tools from Sage Science … more »

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Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

Posted on April 6, 2015 by Alex

February 2015 Authors: Francine E. Garrett-Bakelman, Caroline K. Sheridan, Thadeous J. Kacmarczyk, Jennifer Ishii, Doron Betel, Alicia Alonso, Christopher E. Mason, Maria E. Figueroa, and Ari M. Melnick Info: In this publication in the Journal of Visualized Experiments, scientists at … more »

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Assessing the utility of whole genome amplified DNA for next-generation molecular ecology

Posted on March 3, 2015 by Alex

February 2015 Authors: Christopher Blair, C. Ryan Campbell, and Anne D. Yoder Info: Scientists at Duke University explored whether whole-genome amplification leads to sequence bias by performing a ddRAD-seq study of grey mouse lemurs using multiple displacement amplification. They conclude … more »

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Novel Approach to Quieting MYC Shows Potential for Cancer Treatment

Posted on December 11, 2014 by Alex

It’s hard to have an understated response to seeing our products used in the field when the papers coming out of the work are as extraordinary as this new study from Rick Young at the Whitehead Institute and his collaborators … more »

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ASHG 2014: See You in San Diego!

Posted on October 16, 2014 by Alex

We can’t wait for the annual conference for the American Society of Human Genetics in San Diego this weekend! Five days of back-to-back scientific sessions, 6,500 attendees, countless parties — it’s a great opportunity to geek out on genomics. While … more »

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Illumina Workflow: Pippin for Improved Assembly Accuracy

Posted on October 14, 2014 by Alex

As we’ve seen throughout this blog series, Sage customers are conducting all sorts of great experiments pairing their Pippin size selection instruments with Illumina sequencers. Today we look at the final topic in this thread: boosting assembly accuracy with precise … more »

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Placental miR-1301 is dysregulated in early-onset preeclampsia and inversely correlated with maternal circulating leptin

Posted on October 2, 2014 by Alex

September 2014 Authors: M.S. Weedon-Fekjær, Y. Sheng, M. Sugulle, G.M. Johnsen, F. Herse, C.W. Redman, R. Lyle, R. Dechend, A.C. Staff Info: Scientists from Norway, the UK, and Germany used sequenced small RNAs in placenta from patients with and without … more »

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Evaluation of a Pyrenophora teres f. teres mapping population reveals multiple independent interactions with a region of barley chromosome 6H

Posted on October 2, 2014 by Alex

August 2014 Authors: Rachel A. Shjerve, Justin D. Faris, Robert S. Brueggeman, Changhui Yan, Ya Zhu, Vaidehi Koladia, Timothy L. Friesen Info: Researchers in North Dakota studied the genetics of virulence in a fungal pathogen that affects barley. They looked … more »

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Genetic mapping of horizontal stripes in Lake Victoria cichlid fishes: benefits and pitfalls of using RAD markers for dense linkage mapping

Posted on October 2, 2014 by Alex

August 2014 Authors: Frederico Henning, Hyuk Je Lee, Paolo Franchini and Axel Meyer Info: Scientists from the University of Konstanz in Germany use double-digest RADseq to determine the genetic basis for horizontal stripes seen on cichlid fishes. Sequencing was performed … more »

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