Tag Archives: Pippin Prep

Genome Editing Shows Potential for Shrinking Repeat Expansions

Posted on May 9, 2014 by Alex

Several diseases, many of them involving neurological symptoms, have been linked to expansions of trinucleotide repeat sequences. These repeat expansion disorders include Fragile X syndrome, Huntington’s disease, and various forms of epilepsy and ataxia. In Fragile X, for example, a … more »

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In the Journals: Pippin Publications

Posted on April 10, 2014 by Alex

We’re pleased to see that the steady stream of publications citing the use of Pippin Prep and BluePippin as our automated DNA size selection tools help more and more users get more accurate and reproducible results. The instruments have been … more »

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Highly Specific Contractions of a Single CAG/CTG Trinucleotide Repeat by TALEN in Yeast

Posted on April 8, 2014 by Alex

April 2014 Authors: Guy-Franck Richard, David Viterbo, Varun Khanna, Valentine Mosbach, Lauriane Castelain, and Bernard Dujon Info: Researchers in France used a TALEN to introduce a double-strand break in a CAG/CCTG repeat in yeast cells, finding that doing so deleted … more »

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The emerging biofuel crop Camelina sativa retains a highly undifferentiated hexaploid genome structure

Posted on April 8, 2014 by Alex

April 2014 Authors: Sateesh Kagale, Chushin Koh, John Nixon, Venkatesh Bollina, Wayne E. Clarke, Reetu Tuteja, Charles Spillane, Stephen J. Robinson, Matthew G. Links, Carling Clarke, Erin E. Higgins, Terry Huebert, Andrew G. Sharpe & Isobel A.P. Parkin Info: Scientists … more »

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Genome-wide SNPs lead to strong signals of geographic structure and relatedness paterns in the major arbovirus vector, Aedes aegypti

Posted on April 7, 2014 by Alex

April 2014 Authors: Gordana Rašić, Igor Filipović, Andrew R Weeks and Ary A Hoffmann Info: From the Pest and Disease Vector Group, Department of Genetics, the University of Melbourne Australia. The researchers developed a new bioinformatics tool for the ddRAD … more »

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A first genetic map of date palm (Phoenix dactylifera) reveals long-range genome structure conservation in the palms

Posted on April 7, 2014 by Alex

April 2014 Authors: Lisa S Mathew, Manuel Spannagl, Ameena Al-Malki, Binu George, Maria F Torres, Eman K Al-Dous, Eman K Al-Azwani, Emad Hussein, Sweety Mathew, Klaus FX Mayer, Yasmin Ali Mohamoud, Karsten Suhre and Joel A Malek Info: The first … more »

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Detection of 1,25-Dihydroxyvitamin D-Regulated miRNAs in Zebrafish by Whole Transcriptome Sequencing

Posted on March 15, 2014 by Alex

March 2014 (epub ahead of print) Authors: Theodore A. Craig, Yuji Zhang, Andrew T. Magis, Cory C. Funk, Nathan D. Price, Stephen C. Ekker, and Rajiv Kumar Info: In this paper from the journal Zebrafish, scientists report a study of … more »

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DNA methylation is required for the control of stem cell differentiation in the small intestine

Posted on March 8, 2014 by Alex

March 2014 Authors: Karyn L. Sheaffer, Rinho Kim, Reina Aoki, Ellen N. Elliott, Jonathan Schug, Lukas Burger, Dirk Schubeler, and Klaus H. Kaestner Info: Scientists in Switzerland and Pennsylvania sought to understand the role of methylation in stem cell-directed regeneration … more »

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Redefining the Human Oral Mycobiome with Improved Practices in Amplicon-based Taxonomy: Discovery of Malassezia as a Prominent Commensal

Posted on March 8, 2014 by Alex

March 2014 Authors: Amanda K. Dupuy, Marika S. David, Lu Li, Thomas N. Heider, Jason D. Peterson, Elizabeth A. Montano, Anna Dongari-Bagtzoglou, Patricia I. Diaz, Linda D. Strausbaugh Info: In this PLoS One paper, scientists from the University of Connecticut … more »

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Simultaneous Rapid Sequencing of Multiple RNA Virus Genomes

Posted on March 7, 2014 by Alex

March 2014 Authors: John D. Neill, Darrell O. Baylesb, and Julia F. Ridpatha Info: Researchers at the USDA in Ames, Iowa, apply NGS to simultaneously sequence ten genomes of archived viruses from a single pooled sample, with the goal of … more »

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