Tag Archives: oxford nanopore

London Calling: Who Will Beat the 1 Mb Read?

Posted on May 22, 2018 by Alex

Later this week, scientists will descend on Old Billingsgate, London, for Oxford Nanopore’s annual user event. Better known as London Calling, the meeting has become famous for talks full of cutting-edge nanopore sequencing results, novel protocols, and best practices. The … more »

Posted in Blog | Tagged | Comments Off on London Calling: Who Will Beat the 1 Mb Read?

App Note: BluePippin Sizing Yields Longer MinION Reads

Posted on May 17, 2018 by Alex

BluePippin users are generating longer reads from their Oxford Nanopore MinION sequencers, as demonstrated in a new app note from our colleagues at Nippon Genetics. The app note showcases a workflow used by Kazuharu Arakawa, an associate professor in the … more »

Posted in Blog | Tagged , , , | Comments Off on App Note: BluePippin Sizing Yields Longer MinION Reads

Mapping and phasing of structural variation in patient genomes using nanopore sequencing

Posted on November 18, 2017 by Alex

November 2017 Authors: Mircea Cretu Stancu, Markus van Roosmalen, Ivo Renkens, Marleen Nieboer, et al. Info: Scientists used the Oxford MinION nanopore sequencer with a novel pipeline, NanoSV, to detect structural variants from the genomes of two patients. They found … more »

Posted in Citation | Tagged , | Comments Off on Mapping and phasing of structural variation in patient genomes using nanopore sequencing

Preprint Highlights Utility of Size Selection for Nanopore Studies

Posted on June 29, 2017 by Alex

A recently shared preprint demonstrates the effectiveness of size-selection for nanopore sequencing, relying on the PippinHT automated DNA sizing platform for high-throughput pipelines. “Mapping And Phasing Of Structural Variation In Patient Genomes Using Nanopore Sequencing” comes from lead author Mircea … more »

Posted in Blog | Tagged , | Comments Off on Preprint Highlights Utility of Size Selection for Nanopore Studies

Creighton Lab Boosts Yield, Sequencing Efficiency with BluePippin

Posted on June 13, 2017 by Alex

At Creighton University in Omaha, Neb., Dr. Anna Selmecki’s lab explores various fungal species to understand genome instability, pathogenesis, and the acquisition of drug resistance. For these investigations, her team relies heavily on whole genome sequencing, using both the Illumina … more »

Posted in Blog | Tagged , , , | Comments Off on Creighton Lab Boosts Yield, Sequencing Efficiency with BluePippin

Detecting DNA cytosine methylation using nanopore sequencing

Posted on March 25, 2017 by Alex

February 2017 Authors: Jared Simpson, Rachael Workman, PC Zuzarte, Matei David, LJ Dursi & Winston Timp Info: In this paper, scientists report developing algorithms to distinguish methylated from unmethylated DNA using the Oxford Nanopore MinION sequencer. They evaluated its performance … more »

Posted in Citation | Tagged , , | Comments Off on Detecting DNA cytosine methylation using nanopore sequencing

Preprints Galore!

Posted on December 8, 2016 by Alex

We normally wait until papers come out in scientific journals before reporting on them here, but there are so many great preprints featuring Sage Science tools we couldn’t resist pointing them out. (On a side note, the rising numbers of … more »

Posted in Blog | Tagged , , | Comments Off on Preprints Galore!