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Tag Archives: Pippin Prep
1,000th Pippin Customer: Cave Scientist Extraordinaire
At the University of Akron, geology and biology professor Hazel Barton shows her students the ropes. Literally. A veteran caver, Barton combined her passion for exploring some of the most remote locations in the world with her scientific interest in … more »
Posted in Blog
Tagged Pippin Prep
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Multisubstrate Isotope Labeling and Metagenomic Analysis of Active Soil Bacterial Communities
July 2014 Authors: Y. Verastegui, J. Cheng, K. Engel, D. Kolczynski, S. Mortimer, J. Lavigne, J. Montalibet, T. Romantsov, M. Hall, B. J. McConkey, D. R. Rose, J. J. Tomashek, B. R. Scott, T. C. Charles, J. D. Neufeld Info: … more »
Posted in Citation
Tagged Illumina, Pippin Prep
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Single-Step Selection of Bivalent Aptamers Validated by Comparison with SELEX Using High-Throughput Sequencing
June 2014 Authors: Robert Wilson, Christian Bourne, Roy R. Chaudhuri, Richard Gregory, John Kenny, Andrew Cossins Info: This study, conducted by researchers at the University of Liverpool, aimed at accelerating the identification of nucleic acid aptamers by finding ways to … more »
Posted in Citation
Tagged Pippin Prep
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Improved Multiple Displacement Amplification (iMDA) and Ultraclean Reagents
June 2014 Authors: S Timothy Motley, John M Picuri, Chris D Crowder, Jeremiah J Minich, Steven A Hofstadler and Mark W Eshoo Info: In this methods paper, researchers from Ibis Biosciences report a superior whole-genome amplification protocol that can be … more »
Posted in Citation
Tagged Ion Torrent, Methods, Pippin Prep
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Methylation-capture and Next-Generation Sequencing of free circulating DNA from human plasma
June 2014 Authors: Kristina Warton, Vita Lin, Tina Navin, Nicola J Armstrong, Warren Kaplan, Kevin Ying, Brian Gloss, Helena Mangs, Shalima S Nair, Neville F Hacker, Robert L Sutherland, Susan J Clark and Goli Samimi1 Info: This study from the … more »
Posted in Citation
Tagged Featured, Illumina, Methods, Pippin Prep
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SimRAD: a R package for simulation-based prediction of the number of loci expected in RADseq and similar genotyping by sequencing approaches
May 2014 (epub ahead of print) Authors: Olivier Lepais and Jason T Weir Info: This article from Molecular Ecology Resources describes a new software tool designed to help scientists optimize their double-digest RADseq (ddRADseq) experiments by accurately estimating the number … more »
Posted in Citation
Tagged Featured, Pippin Prep, RADseq
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Pippin Enriches for MicroRNAs in Zebrafish Transcriptome Study
Scientists from the Mayo Clinic, Institute for Systems Biology, and University of Illinois recently published a study investigating the effects of vitamin D on microRNA regulation of gene expression in zebrafish. The team used our Pippin Prep together with the … more »
Posted in Blog
Tagged miRNA, miRNA isolation, NEBNext, Pippin Prep
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Genome Editing Shows Potential for Shrinking Repeat Expansions
Several diseases, many of them involving neurological symptoms, have been linked to expansions of trinucleotide repeat sequences. These repeat expansion disorders include Fragile X syndrome, Huntington’s disease, and various forms of epilepsy and ataxia. In Fragile X, for example, a … more »
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Tagged DNA Sequencing, Illumina, Pippin Prep
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In the Journals: Pippin Publications
We’re pleased to see that the steady stream of publications citing the use of Pippin Prep and BluePippin as our automated DNA size selection tools help more and more users get more accurate and reproducible results. The instruments have been … more »
Highly Specific Contractions of a Single CAG/CTG Trinucleotide Repeat by TALEN in Yeast
April 2014 Authors: Guy-Franck Richard, David Viterbo, Varun Khanna, Valentine Mosbach, Lauriane Castelain, and Bernard Dujon Info: Researchers in France used a TALEN to introduce a double-strand break in a CAG/CCTG repeat in yeast cells, finding that doing so deleted … more »
Posted in Citation
Tagged DNA Sequencing, Illumina, Pippin Prep
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