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Tag Archives: microRNA
Micro RNA’s (miRNA’s) may help explain expression of multiple genes in Alzheimer’s Frontal Cortex
September 2017 Authors: James Bennett and Paula Keeney Info: Scientists from Neurodegeneration Therapeutics used RNA-seq to compare microRNAs found in Alzheimer’s brain samples and controls. They identified 55 up-regulated genes and 191 down-regulated genes in the Alzheimer’s samples. PippinHT was … more »
Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice
July 2017 Authors: Justin Quiles, Madhusudhanan Narasimhan, Gobinath Shanmugam, Brett Milash, John Hoidal, and Namakkal Rajasekaran Info: Scientists from the University of Alabama at Birmingham and other institutions studied a gene previously associated with oxidative stress, analyzing differential expression in … more »
Posted in Citation
Tagged HiSeq, microRNA, Pippin Prep
Comments Off on Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice
Co-chaperone Hsp70/Hsp90 organizing protein (Hop) is Required for Transposon Silencing and piRNA Biogenesis
February 2017 Authors: Joseph A. Karam, Rasesh Y. Parikh, Dhananjaya Nayak, David Rosenkranz and Vamsi K. Gangaraju Info: Scientists from South Carolina and Mainz, Germany, studied Hop, a co-chaperone that interacts with a piRNA in Drosophila. They found that knocking … more »
Posted in Citation
Tagged HiSeq, microRNA, miRNA, Pippin Prep
Comments Off on Co-chaperone Hsp70/Hsp90 organizing protein (Hop) is Required for Transposon Silencing and piRNA Biogenesis
Comprehensive evaluation of extracellular small RNA isolation methods from serum in high throughput sequencing
January 2017 Authors: Yan Guo, Kasey Vickers, Yanhua Xiong, Shilin Zhao, Quanhu Sheng, Pan Zhang, Wanding Zhou and Charles R. Flynn Info: Scientists from Vanderbilt University and Van Andel Research Institute compared methods for isolating circulating extracellular small non-coding RNAs. … more »
Posted in Citation
Tagged microRNA, miRNA, NextSeq, Pippin Prep
Comments Off on Comprehensive evaluation of extracellular small RNA isolation methods from serum in high throughput sequencing
The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity
December 2016 Authors: Samer G. Alam, Qiao Zhang, Nripesh Prasad, Yuan Li, Srikar Chamala, et al. Info: Researchers from the HudsonAlpha Institute, the University of Florida, and other institutions studied the role of rigidity in the extracellular matrix, finding that … more »
Posted in Citation
Tagged microRNA, Pippin Prep
Comments Off on The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity
Depletion of tRNA-halves enables effective small RNA sequencing of low-input murine serum samples
November 2016 Authors: Alan Van Goethem, Nurten Yigit, Celine Everaert, Myrthala Moreno-Smith, et al. Info: Scientists at Ghent University and Baylor College of Medicine evaluated protocols for depleting abundant RNAs from blood and serum samples to improve the ability to … more »
Posted in Citation
Tagged microRNA, Pippin Prep
Comments Off on Depletion of tRNA-halves enables effective small RNA sequencing of low-input murine serum samples
Association of MicroRNAs with Antibody Response to Mycoplasma bovis in Beef Cattle
August 2016 Authors: Eduardo Casas, Guohong Cai, Larry A. Kuehn, Karen B. Register, Tara G. McDaneld, John D. Neill Info: USDA scientists performed a longitudinal study of young cows to identify microRNAs linked to a serum antibody produced after exposure … more »
Posted in Citation
Tagged HiSeq, Illumina, microRNA, Pippin Prep, RNA sequencing
Comments Off on Association of MicroRNAs with Antibody Response to Mycoplasma bovis in Beef Cattle
For MicroRNA Discovery, Pippin Prep Delivers Highest Yield and Specificity
In a highly accessed paper in BMC Medical Genomics, scientists from McGill University and EMBL tested several steps to find the most robust pipeline for discovering small non-coding RNAs (sncRNAs) that might be useful as biomarkers. As part of this … more »
Posted in Blog
Tagged microRNA, miRNA, miRNA isolation, Pippin Prep
Comments Off on For MicroRNA Discovery, Pippin Prep Delivers Highest Yield and Specificity