Multi-omics maps of cotton fibre reveal epigenetic basis for staged single-cell differentiation

April 2016

Maojun Wang, Pengcheng Wang, Lili Tu, Sitao Zhu, Lin Zhang, Zhonghua Li, Qinghua Zhang, Daojun Yuan, and Xianlong Zhang

Scientists from Huazhong Agricultural University in China studied the epigenetics of single-cell differentiation

in cotton, finding clear patterns of DNA methylation during development. They used PippinHT to isolate 100 bp – 200 bp fragments which were run in MNase-seq and ChIP-seq pipelines on an Illumina HiSeq 3000.

Nucleic Acids Research, 2016
doi: 10.1093/nar/gkw238

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