Yearly Archives: 2014

2014 in the Rearview Mirror

Posted on December 18, 2014 by Alex

The holiday season always triggers some nostalgia, and here at Sage Science headquarters we’re thinking about what a big year 2014 has been for us. We hit some big milestones, including our 1,000th Pippin customer, moving to larger office space … more »

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New PacBio Isoform Sequencing Protocol Recommends SageELF

Posted on December 18, 2014 by Alex

If you’re performing isoform sequencing on the PacBio platform, check out this protocol. PacBio recommends size fractionation of cDNAs into four pooled fractions using our SageELF. There’s also an optional step in the protocol for larger libraries to use SageELF … more »

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Novel Approach to Quieting MYC Shows Potential for Cancer Treatment

Posted on December 11, 2014 by Alex

It’s hard to have an understated response to seeing our products used in the field when the papers coming out of the work are as extraordinary as this new study from Rick Young at the Whitehead Institute and his collaborators … more »

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Strides in Fighting Cancer, Plus BluePippin in Primetime

Posted on December 8, 2014 by Alex

It’s not every day you turn on 60 Minutes and see your own product on the screen. In last night’s episode, the news show profiled Los Angeles billionaire Patrick Soon-Shiong, whose array of companies is tackling everything from data storage … more »

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New Look at Complexity in the Human Genome Uses BluePippin for Sizing

Posted on December 3, 2014 by Alex

We’ve been fans of Evan Eichler’s since the earliest days of his work in segmental duplication and genome hotspots — so it’s great to see that he’s at it again. In this new Nature paper, Eichler and lead author Mark … more »

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CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer

Posted on November 18, 2014 by Alex

November 2014 Authors: Edmond Chipumuro, Eugenio Marco, Camilla L. Christensen, Nicholas Kwiatkowski, Tinghu Zhang,Clark M. Hatheway, Brian J. Abraham, Bandana Sharma, Caleb Yeung, Abigail Altabef, Antonio Perez-Atayde, Kwok-Kin Wong, Guo-Cheng Yuan, Nathanael S. Gray, Richard A. Young, and Rani E. … more »

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Resolving the complexity of the human genome using single-molecule sequencing

Posted on November 18, 2014 by Alex

November 2014 Authors: Mark J. P. Chaisson, John Huddleston, Megan Y. Dennis, Peter H. Sudmant, Maika Malig, Fereydoun Hormozdiari, Francesca Antonacci, Urvashi Surti, Richard Sandstrom, Matthew Boitano, Jane M. Landolin, John A. Stamatoyannopoulos, Michael W. Hunkapiller, Jonas Korlach & Evan … more »

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PacBio User Meeting: Size Selection for Best Results

Posted on November 17, 2014 by Alex

Last month we got to attend PacBio’s user group meeting in Palo Alto, Calif. Sage Science co-sponsored the event, as we have in the past, because the PacBio community is doing some extraordinary work with size selection and we’re always … more »

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Sage Science Launches High-Throughput DNA Sizing Platform for NGS Workflow

Posted on November 11, 2014 by Alex

BEVERLY, Mass. — November 11, 2014 — Sage Science, a developer of life science products for improving sample preparation processes in molecular biology applications, today introduced the PippinHT, a high-throughput version of the popular Pippin line of automated DNA size … more »

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You Asked for It: Pippin Goes High-Throughput!

Posted on November 11, 2014 by Alex

Welcome to the family, PippinHT. Today we’re proud to be launching the high-throughput version of our automated DNA sizing platform for NGS workflows. PippinHT can run as many as 24 samples at a time, with half the run time of … more »

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