Long-read sequencing and de novo assembly of a Chinese genome

June 2016

Lingling Shi, Yunfei Guo, Chengliang Dong, John Huddleston, Hui Yang, et al.

Scientists in China and the US analyzed the DNA and RNA of a Chinese individual, using PacBio sequencing and BioNano Genomics maps to produce a high-quality assembly. They report a significant amount of new sequence data and novel gene content, including elements that appear to be specific to the Asian population. The team used BluePippin for size selection prior to genome and transcriptome sequencing with PacBio.

Nature Communications

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