Circulating Extracellular RNA Markers of Liver Regeneration

July 2016

Irene K. Yan, Xue Wang, Yan W. Asmann, Hiroaki Haga, Tushar Patel

Mayo Clinic researchers performed partial hepatectomies in mice and then monitored RNA activity in serum samples to find a signature associated with liver regeneration. They found detectable changes in small non-coding RNAs such as microRNA, snoRNA, tRNA, and more. The team used Pippin Prep to fractionate RNA libraries prior to sequencing with Illumina MiSeq.

PLoS ONE 11(7): e0155888.

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