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Recent Posts
- The haplotype-resolved T2T carnation (Dianthus caryophyllus) genome reveal the correlation between genome architecture and gene expression
- “Range+T “ for Tight Sizing of HMW Libraries
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- The draft genome sequence of the Japanese rhinoceros beetle Trypoxylus dichotomus septentrionalis towards an understanding of horn formation
- Targeted Phasing of 2-200 Kilobase DNA Fragments with a Short-Read Sequencer and a Single-Tube Linked-Read Library Method
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Category Archives: Blog
Expert Q&A: Winston Timp on New Challenges in Sample Prep
We’re learning as we go: that’s the message from Winston Timp, assistant professor at Johns Hopkins University, about how labs are handling the new demands placed on sample prep techniques by ever-changing sequencing technologies. Timp’s impressive results, particularly with handling … more »
Cost-Effective Microbiome Sequencing with 10x Genomics and Athena Assembler
If you missed Ami Bhatt’s talk at AGBT last month, a bioRxiv preprint is a great way to catch up on her team’s impressive work characterizing microbial communities — from the human gut to the sea floor. Bhatt and her … more »
Posted in Blog
Tagged 10x Genomics, BluePippin, microbiome
Comments Off on Cost-Effective Microbiome Sequencing with 10x Genomics and Athena Assembler
Podcast: Blogger Keith Robison on the State of Sequencing
A new podcast from Mendelspod takes a look at the state of sequencing in 2018. It’s a lively and interesting discussion about the current and future landscape of genomics between host Theral Timpson and Keith Robison, founder of the Omics! … more »
At AGBT, Scientists Offer Data on Size Selection for HMW DNA
Even Orlando’s sky-high humidity can’t get us down during a fast-paced AGBT meeting where size selection and HMW DNA have been front and center since the opening session. Last night we enjoyed a plenary talk from Ami Bhatt, a scientist … more »
SageELF Enables Targeted RenSeq Capture for PacBio Sequencing
We’ve had targeted capture on the brain lately as we work with collaborators to put the finishing touches on our HLS-CATCH method for selecting large genomic elements using Cas9 guides and the SageHLS system. So today, we wanted to revisit … more »
Fireworks, Genomics, and HLS-CATCH at AGBT in Orlando
The regular Super Bowl may have gone down last weekend, but the genomics Super Bowl is still to come with next week’s Advances in Genome Biology & Technology meeting in Orlando. The Sage Science team can’t wait. AGBT is our … more »
Expert Q&A: Smithsonian Scientists on Evaluating DNA Quality
With the rapid adoption of long-read sequencing and other technologies that require high molecular weight DNA input, there is rising demand for high-quality samples from biorepositories around the world. To accommodate this, scientists at the Smithsonian Institution’s National Museum of … more »
San Diego Is Calling: Are You Ready for PAG?
It’s the start of a bright, shiny new year. If you’ve been in the genomics field long enough, you know that can mean only one thing: we’re getting ready for PAG! Officially the Plant and Animal Genome XXVI Conference, this … more »
New Mosquito Assembly to Accelerate Science and Insect Control
There’s a lot to love about the new preprint announcing the first-ever truly high-quality reference genome assembly for the Aedes aegypti mosquito. The large consortium of scientists — the paper features a total of 72 co-authors — came together on … more »
Posted in Blog
Tagged BluePippin, PacBio, SageELF
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A Look Back at 2017
As we start to make lists of New Year’s resolutions (with bets on how long they’ll last), it’s the perfect time for a moment to absorb the themes and highlights of 2017. In our corner of the world, that means … more »