Category Archives: Blog

Expert Q&A: Winston Timp on New Challenges in Sample Prep

Posted on March 27, 2018 by Alex

We’re learning as we go: that’s the message from Winston Timp, assistant professor at Johns Hopkins University, about how labs are handling the new demands placed on sample prep techniques by ever-changing sequencing technologies. Timp’s impressive results, particularly with handling … more »

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Cost-Effective Microbiome Sequencing with 10x Genomics and Athena Assembler

Posted on March 21, 2018 by Alex

If you missed Ami Bhatt’s talk at AGBT last month, a bioRxiv preprint is a great way to catch up on her team’s impressive work characterizing microbial communities — from the human gut to the sea floor. Bhatt and her … more »

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Podcast: Blogger Keith Robison on the State of Sequencing

Posted on February 27, 2018 by Alex

A new podcast from Mendelspod takes a look at the state of sequencing in 2018. It’s a lively and interesting discussion about the current and future landscape of genomics between host Theral Timpson and Keith Robison, founder of the Omics! … more »

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At AGBT, Scientists Offer Data on Size Selection for HMW DNA

Posted on February 13, 2018 by Alex

Even Orlando’s sky-high humidity can’t get us down during a fast-paced AGBT meeting where size selection and HMW DNA have been front and center since the opening session. Last night we enjoyed a plenary talk from Ami Bhatt, a scientist … more »

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SageELF Enables Targeted RenSeq Capture for PacBio Sequencing

Posted on February 13, 2018 by Alex

We’ve had targeted capture on the brain lately as we work with collaborators to put the finishing touches on our HLS-CATCH method for selecting large genomic elements using Cas9 guides and the SageHLS system. So today, we wanted to revisit … more »

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Fireworks, Genomics, and HLS-CATCH at AGBT in Orlando

Posted on February 8, 2018 by Alex

The regular Super Bowl may have gone down last weekend, but the genomics Super Bowl is still to come with next week’s Advances in Genome Biology & Technology meeting in Orlando. The Sage Science team can’t wait. AGBT is our … more »

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Expert Q&A: Smithsonian Scientists on Evaluating DNA Quality

Posted on January 29, 2018 by Alex

With the rapid adoption of long-read sequencing and other technologies that require high molecular weight DNA input, there is rising demand for high-quality samples from biorepositories around the world. To accommodate this, scientists at the Smithsonian Institution’s National Museum of … more »

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San Diego Is Calling: Are You Ready for PAG?

Posted on January 9, 2018 by Alex

It’s the start of a bright, shiny new year. If you’ve been in the genomics field long enough, you know that can mean only one thing: we’re getting ready for PAG! Officially the Plant and Animal Genome XXVI Conference, this … more »

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New Mosquito Assembly to Accelerate Science and Insect Control

Posted on January 5, 2018 by Alex

There’s a lot to love about the new preprint announcing the first-ever truly high-quality reference genome assembly for the Aedes aegypti mosquito. The large consortium of scientists — the paper features a total of 72 co-authors — came together on … more »

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A Look Back at 2017

Posted on December 18, 2017 by Alex

As we start to make lists of New Year’s resolutions (with bets on how long they’ll last), it’s the perfect time for a moment to absorb the themes and highlights of 2017. In our corner of the world, that means … more »

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