Tag Archives: PippinHT

Quantitative detection of low-abundance somatic structural variants in normal cells by high-throughput sequencing

Posted on July 21, 2016 by Alex

June 2016 Authors: Wilber Quispe-Tintaya, Tatyana Gorbacheva, Moonsook Lee, Sergei Makhortov, Vasily N Popov, Jan Vijg & Alexander Y Maslov Info: Scientists report Structural Variant Search, a new method for detecting rare somatic structural variants even with low-coverage sequencing data. … more »

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Sage Sizing Platforms Recommended for 10x Genomics Libraries

Posted on July 18, 2016 by Alex

We’re pleased to report that 10x Genomics has released a new sample prep protocol for its Chromium platform that includes the BluePippin and PippinHT size selection platforms from Sage Science. 10x Genomics has gotten a lot of attention in recent … more »

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Spotted in the Literature: The First PippinHT Publication!

Posted on May 9, 2016 by Alex

We began shipping the high-throughput version of our automated Pippin DNA size selection platform last year, and it’s a thrill to see what we believe is the first reference to it in a peer-reviewed publication. A team of scientists from … more »

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Multi-omics maps of cotton fibre reveal epigenetic basis for staged single-cell differentiation

Posted on May 9, 2016 by Alex

April 2016 Authors: Maojun Wang, Pengcheng Wang, Lili Tu, Sitao Zhu, Lin Zhang, Zhonghua Li, Qinghua Zhang, Daojun Yuan, and Xianlong Zhang Info: Scientists from Huazhong Agricultural University in China studied the epigenetics of single-cell differentiation in cotton, finding clear … more »

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Evidence for the Dizzying Pace of Progress in Genomics

Posted on October 21, 2015 by Alex

The genomics field is a funny place: at times it feels like we’re not making progress quickly enough, and at other times things seem to be moving so fast we’re just holding on for dear life. We were reminded of … more »

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At Einstein Med School, ‘Extremely Reproducible’ Pippin Platforms Save Time and Money

Posted on May 19, 2015 by Alex

In the genetics department at Albert Einstein College of Medicine, Research Assistant Professor Alex Maslov is working to understand structural variants associated with aging and cancer. Using human and mouse cells, he deploys whole genome sequencing to make these links. … more »

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PippinHT in the Wild: High-Throughput ChIP-Seq at Whitehead Core Lab

Posted on April 20, 2015 by Alex

At the Whitehead Institute’s Genome Technology Core, scientists handle a lot of ChIP-seq and RNA-seq projects. To boost capacity in library prep, they recently upgraded from a small fleet of Pippin Prep instruments to the new PippinHT for high-throughput, automated … more »

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Reflecting on ABRF and Experimental Bio: Two Great Events!

Posted on April 2, 2015 by Alex

This week was a busy and educational one for the Sage Science team — we got to attend both the Association of Biomolecular Resource Facilities meeting in St. Louis and the Experimental Biology meeting here in Boston. We had booths … more »

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2015: The Year of Long Reads?

Posted on March 19, 2015 by Alex

We couldn’t help noticing that “long reads” kept popping up in presentations and posters at AGBT, and we certainly weren’t alone. Aside from longtime long-read provider Pacific Biosciences and synthetic long-read service Moleculo, acquired by Illumina in 2012, new companies … more »

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AGBT 2015: You Bring Last Year’s Backpack, We’ll Bring the Popcorn and PippinHT

Posted on February 19, 2015 by Alex

Next week is the biggest party of the year for the genomics community: the Advances in Genome Biology and Technology meeting. The Sage Science team can’t wait to emerge from our Boston igloos to soak up some much-needed warmth in … more »

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