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Tag Archives: cell-free DNA
Heat selection enables highly scalable methylome profiling in cell-free DNA for noninvasive monitoring of cancer patients
September 2022 Authors: Elsie Cheruba, Ramya Viswanathan, Pui-Mun Wong, Howard John Womersley, Shuting Han, Brenda Tay, Yiting Lau, Anna Gan, Polly S. Y. Poon, Anders Skanderup, Sarah B. Ng, Aik Yong Chok, Dawn Qingqing Chong, Iain Beehuat Tan, Lih Feng … more »
Posted in Citation
Tagged bisulfite sequencing, BluePippin, cell-free DNA, Illumina, methylation
Comments Off on Heat selection enables highly scalable methylome profiling in cell-free DNA for noninvasive monitoring of cancer patients
Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
April 2021 Authors: Multiple authors, the SEQC2 Oncopanel Sequencing Working Group Info: A multi-site and cross-platform evaluation of circulating tumor DNA (ctDNA) NGS assays was conducted by the SEQC2 Oncopanel Sequencing Working Group and reported on in this comprehensive study. … more »
Posted in Citation
Tagged cell-free DNA, circulation tumor DNA, ctDNA, Pippin Prep
Comments Off on Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
Circulating Tumor DNA Easier to Spot with Size Selection
A bioRxiv preprint from scientists at Cancer Research UK and Cambridge University Hospitals offers a look at how DNA size selection can be used to enhance results of circulating tumor DNA studies. Their analysis indicates that adding a simple sizing … more »
Posted in Blog
Tagged cell-free DNA, ctDNA, PippinHT
Comments Off on Circulating Tumor DNA Easier to Spot with Size Selection
Poster: Better Cell-Free DNA Analysis with Pippin + Rubicon Genomics
Recently we blogged about the rise of cell-free DNA studies, and how precise size selection is one tool that can help researchers isolate DNA of interest for further analysis (such as sorting out fetal from maternal genetic material). At the AGBT … more »
Posted in Blog
Tagged cell-free DNA, low-pass
Comments Off on Poster: Better Cell-Free DNA Analysis with Pippin + Rubicon Genomics
Size Selection Has Utility for Cell-Free DNA Studies
The rise of research studies and diagnostic tests looking at cell-free DNA — particularly fetal DNA in a mother’s bloodstream — has happened with astonishing speed. Prenatal genetic testing, for instance, has already supplanted many invasive clinical tests such as … more »
Posted in Blog
Tagged cell-free DNA
Comments Off on Size Selection Has Utility for Cell-Free DNA Studies