February 2017
Authors:
Brian J. Abraham, Denes Hnisz, Abraham S. Weintraub, Nicholas Kwiatkowski, et al.
Info:
In this paper, scientists report using ChIP-seq to better understand the role of non-coding somatic insertions in tumorigenesis. They identified enhancer-associated small insertions, often near oncogenes. Pippin Prep was used in the ChIP-seq protocol to capture 200 bp – 400 bp fragments ahead of sequencing on an Illumina HiSeq 2500.
Citation:
Nature Communications
doi:10.1038/ncomms14385