Monthly Archives: June 2015

Festival of Genomics: A New Breed of Conference Kicks Off

Posted on June 29, 2015 by Alex

Last week we attended the first-ever Festival of Genomics, a new series of meetings taking place in Boston, San Mateo, and London. This conference was held in Boston’s biggest convention center, and featured a music festival kind of approach, with … more »

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Sequencing Podcast: Better DNA Extraction Needed for Large-Fragment Libraries

Posted on June 19, 2015 by Alex

If you haven’t listened yet to the Mendelspod interview with Bobby Sebra from the Icahn Institute for Genomics and Multiscale Biology at Mount Sinai, we can’t recommend it highly enough. And that’s not because we happen to be sponsoring this … more »

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Learning About Long Reads: The PacBio User Group Meeting

Posted on June 15, 2015 by Alex

This week we’re traveling to Baltimore for the annual east coast user group meeting for Pacific Biosciences customers. We’re a sponsor of the event and look forward to the great scientific presentations these meetings have become known for. Click here … more »

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Modified Mate-Pair Protocol Lowers Cost, Boosts Library Yield

Posted on June 11, 2015 by Alex

Regular readers of the Sage Science blog know that we can never resist a good methods paper. We enjoyed this publication from the phyloinformatics group at RIKEN detailing a modified protocol for generating high-quality mate-pair libraries while significantly reducing costs. … more »

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Limitations of Climatic Data for Inferring Species Boundaries: Insights from Speckled Rattlesnakes

Posted on June 5, 2015 by Alex

June 2015 Authors: Jesse M. Meik, Jeffrey W. Streicher, A. Michelle Lawing, Oscar Flores-Villela, and Matthew K. Fujita Info: In this paper, scientists in Texas and Mexico challenge conventional climate-based species boundaries in the speckled rattlesnake, using genomic and other … more »

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Fecal virome analysis of three carnivores reveals a novel nodavirus and multiple gemycircularviruses

Posted on June 4, 2015 by Alex

May 2015 Authors: Nádia Conceição-Neto, Mark Zeller, Elisabeth Heylen, Hanne Lefrère, João Rodrigo Mesquita and Jelle Matthijnssens Info: This publication in Virology Journal describes metagenomics analyses of fecal samples from badger, mongoose, and otter to better understand viral populations in … more »

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Optimization and cost-saving in tagmentation-based mate-pair library preparation and sequencing

Posted on June 3, 2015 by Alex

May 2015 Authors: Kaori Tatsumi, Osamu Nishimura, Kazu Itomi, Chiharu Tanegashima, and Shigehiro Kuraku Info: Scientists from RIKEN modified the recommended protocol for the Nextera Mate Pair Sample Prep Kit from Illumina to improve library yield and quality while minimizing … more »

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NGS Technologies Offer Accurate, Affordable Alternative for HLA Typing

Posted on June 3, 2015 by Alex

We always knew genomics would have a positive impact on healthcare, but as we were dreaming about tailored therapies, targeted cancer treatments, and preventive medicine based on known susceptibilities, there was one area we didn’t think about: HLA typing. It’s … more »

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