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Recent Posts
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- Identifying the best PCR enzyme for library amplification in NGS
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Tag Archives: SageHLS
SageHLS Helps Unravel the Neuropsychiatric 22q11.2 Deletion Region1q11
An international collaboration led by the Stanford labs of Alexander Urban and Hanlee Ji, used the SageHLS system to map a Mb-sized deletion in a complex region of the human genome, 22q11.2, that is associated with a variety of neurodevelopmental … more »
Podcast: HMW DNA, Personalized Cancer Vaccines, and Structural Variation
There’s a great new podcast interview with Stanford clinical geneticist and oncologist Hanlee Ji about targeting extremely large stretches of DNA by combining CRISPR methods, automated DNA purification with the SageHLS instrument, and 10x Genomics technology. The approach works with … more »
Fireworks, Genomics, and HLS-CATCH at AGBT in Orlando
The regular Super Bowl may have gone down last weekend, but the genomics Super Bowl is still to come with next week’s Advances in Genome Biology & Technology meeting in Orlando. The Sage Science team can’t wait. AGBT is our … more »
A Look Back at 2017
As we start to make lists of New Year’s resolutions (with bets on how long they’ll last), it’s the perfect time for a moment to absorb the themes and highlights of 2017. In our corner of the world, that means … more »
ASHG 2017: Big Studies, Big Names, and Big DNA
We can’t wait for the annual meeting of the American Society of Human Genetics next week! The Sage Science team will be heading to Orlando to catch up on cutting-edge genome science with several thousand of our nearest and dearest … more »
PacBio Users: Size Selection Is Essential for Generating Excellent Results
The Sage Science team was delighted to attend and co-sponsor PacBio’s annual East Coast user group meeting in Baltimore last week, particularly since there was a half-day session devoted to our favorite subject: sample prep. There were plenty of customer … more »
How to CATCH Your Gene of Interest
If you haven’t heard about CATCH by now, it’s time to catch up. Short for Cas9-assisted targeting of chromosome segments, CATCH comes from the lab of Yuval Ebenstein at Tel Aviv University and was first reported in this Nature Communications … more »
Q&A: How SageHLS Brings Back the ‘Lost Art’ of HMW DNA Prep
Chris Boles is Chief Scientific Officer of Sage Science, where he’s been helping the R&D team develop the new SageHLS (that’s short for HMW Library System), a platform designed to rapidly purify high molecular weight DNA directly from samples. We … more »
The Darling of AGBT: HMW DNA
The Sage Science team had a blast at this year’s AGBT conference in Hollywood, Fla. We thoroughly enjoyed the parties, the beach, and especially the excellent talks. We’d like to thank all of the attendees who made their way to … more »
Calling All Technophiles: Time for AGBT!
The Sage Science team is casting off the shackles of winter and gearing up for a trip to sunny Florida for the annual Advances in Genome Biology and Technology meeting. We look forward to this conference each year — it’s … more »