Tag Archives: PacBio

A multidrug resistance plasmid contains the molecular switch for type VI secretion in Acinetobacter baumannii

July 2015 Authors: Brent S. Weber, Pek Man Ly, Joshua N. Irwin, Stefan Pukatzki, Mario F. Feldman Info: Scientists from the University of Alberta and Washington University published results in PNAS showing that a large plasmid is important to Acinetobacter … more »

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Podcast: Cornell’s Chris Mason on Sequencing, Subways, and Outer Space

If you’re looking for out-there ideas in genomics, there’s no better place to start than with Chris Mason’s lab at Weill Cornell Medical College. We were delighted that Mason was featured in the latest podcast from Mendelspod and its host … more »

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Churning Out New Microbial Genome Sequences

PacBio users have been regularly serving up new microbial genome assemblies, and we’re glad to see that they’re using our BluePippin automated DNA size selection instrument to get the best results. These are just some of the genome announcements published … more »

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Assembly and diploid architecture of an individual human genome via single-molecule technologies

June 2015 Authors: Matthew Pendleton, Robert Sebra, Andy Wing Chun Pang, Ajay Ummat, Oscar Franzen, Tobias Rausch, Adrian M Stütz, William Stedman, Thomas Anantharaman, Alex Hastie, Heng Dai, Markus Hsi-Yang Fritz, Han Cao, Ariella Cohain, Gintaras Deikus, Russell E Durrett, … more »

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Hybrid Single-Molecule Approach Produces Highly Contiguous Diploid Human Genome Assembly

A team of scientists from the Icahn School of Medicine at Mount Sinai, Weill Cornell Medical College, Cold Spring Harbor Laboratory, European Molecular Biology Laboratory, and other institutions published the first analysis of a diploid human genome produced by combining … more »

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Learning About Long Reads: The PacBio User Group Meeting

This week we’re traveling to Baltimore for the annual east coast user group meeting for Pacific Biosciences customers. We’re a sponsor of the event and look forward to the great scientific presentations these meetings have become known for. Click here … more »

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Assessing structural variation in a personal genome—towards a human reference diploid genome

April 2015 Authors: Adam C English, William J Salerno, Oliver A Hampton, Claudia Gonzaga-Jauregui, Shruthi Ambreth, Deborah I Ritter, Christine R Beck, Caleb F Davis, Mahmoud Dahdouli, Singer Ma, Andrew Carroll, Narayanan Veeraraghavan, Jeremy Bruestle, Becky Drees, Alex Hastie, Ernest … more »

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New Structural Variant Analysis Method Uses Targeted Capture and Sequencing of Large-Insert DNA

In a new BMC Genomics paper, scientists from Baylor College of Medicine describe a new method for accurate, affordable interrogation of structural variants across the human genome. We’re delighted to see that automated DNA size selection tools from Sage Science … more »

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Still Buzzing about the Coffee Talk at PAG

One of our favorite sessions at last week’s PAG meeting focused on a major sequencing effort to understand the coffee genome. The presentation, from scientists at Cenicafé (Colombia’s National Coffee Research Center) highlighted a new project designed to characterize elements … more »

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Large DNA in the Spotlight at PAG 2015

This year’s PAG meeting featured the usual treats of interesting organisms being sequenced (koala!), reports from great plant and animal projects, and cool new technology approaches. While we found all of it fascinating, the theme of the meeting for us … more »

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