DSBCapture: in situ capture and sequencing of DNA breaks

August 2016

Authors:

Stefanie V Lensing, Giovanni Marsico, Robert Hänsel-Hertsch, Enid Y Lam, David Tannahill & Shankar Balasubramanian

Info:
Scientists at Cancer Research UK developed and validated a new sequencing-based protocol to spot double-stranded DNA breaks in situ; these regions are important for study because they contribute to mutations and chromosomal rearrangements. The method includes performing size selection on a BluePippin prior to sequencing

Citation:
Nature Methods (2016)
doi:10.1038/nmeth.3960

This entry was posted in Citation and tagged , , , , . Bookmark the permalink.

Comments are closed.