Arterial endothelial methylome: differential DNA methylation in athero-susceptible disturbed flow regions in vivo

July 2015

Yi-Zhou Jiang, Elisabetta Manduchi, Christian J. Stoeckert, and Peter F. Davies

In this paper, scientists from the University of Pennsylvania used complete methylated DNA immunoprecipitation sequencing (MeDIP-seq) to study methylation differences in endothelial cells to find clues about atherosclerosis susceptibility. The team used Pippin Prep to size-select MeDIP libraries prior to Illumina sequencing.

BMC Genomics 2015, 16:506

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