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Recent Posts
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- In vitro size-selection of short circulating tumor DNA fragments from late-stage lung cancer patients enhance the detection of mutations and aneuploidies
- The haplotype-resolved T2T carnation (Dianthus caryophyllus) genome reveal the correlation between genome architecture and gene expression
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Author Archives: Alex
Extensive sequencing of seven human genomes to characterize benchmark reference materials
June 2016 Authors: Justin M. Zook, David Catoe, Jennifer McDaniel, Lindsay Vang, et al. Info: The Genome in a Bottle Consortium used 12 different DNA analysis technologies to generate deep data sets on seven genomes, five of which will become … more »
Posted in Citation
Tagged BluePippin, PacBio
Comments Off on Extensive sequencing of seven human genomes to characterize benchmark reference materials
NCSU Scientist Incorporates Genomics for Better Blueberry Resources
Hamid Ashrafi is working to breed higher-quality blueberries that are amenable to mechanical harvest, larger in size, tastier, and have a longer shelf life. As an assistant professor at North Carolina State University, Ashrafi is bringing genomic tools to a … more »
Posted in Blog
Tagged BluePippin, isoseq, PacBio, SageELF
Comments Off on NCSU Scientist Incorporates Genomics for Better Blueberry Resources
SageELF Offers Unique Advantages for Long-Range Sequencing and CNV Analysis
We released our SageELF instrument two years ago, and seeing how scientists have adopted it for various NGS pipelines has been a wonderful journey. If you haven’t noticed these great uses, we’ll get you up to speed with this quick … more »
A highly robust and optimized sequence-based approach for genetic polymorphism discovery and genotyping in large plant populations
May 2016 Authors: Ning Jiang, Fengjun Zhang, Jinhua Wu, Yue Chen, Xiaohua Hu, Ou Fang, Lindsey J. Leach, Di Wang, Zewei Luo Info: Scientists in China and the UK developed an optimized RAD-seq protocol that delivers better uniformity of genome … more »
The Conference Month: Prepping for PacBio, ASM, FoG
It’s June, and you know what that means: genomics conference season is back! The Sage team will be attending several events this month and we hope to see you at least once. We kick off next week with PacBio’s annual … more »
For PacBio’s Iso-Seq Method, Users Deploy SageELF or BluePippin Size Selection
More and more scientists are using their PacBio systems for transcriptome studies, generating full-length isoforms with the Iso-Seq method. The number of novel transcripts discovered and the implications for alternative splicing are a not-so-subtle reminder that we still have a … more »
How to Work with Large DNA: Data from the Sage HLS Platform
The Sage Science R&D team has been hard at work on our newest tool, to be released later this year. The HLS platform, which we first described at the Festival of Genomics meeting in Boston last year, is our answer … more »
Urban Mice: NYC Study Sheds Light on Population Diversity and Changes
They may make subway riders shudder, but New York City mice are the stars of a cool new paper outlining their evolutionary history during a rapid period of urbanization. Scientists from the City University of New York used ddRAD-seq to … more »
Posted in Blog
Tagged ddRADseq, genotyping, HiSeq, Illumina, Pippin Prep
Comments Off on Urban Mice: NYC Study Sheds Light on Population Diversity and Changes
Spotted in the Literature: The First PippinHT Publication!
We began shipping the high-throughput version of our automated Pippin DNA size selection platform last year, and it’s a thrill to see what we believe is the first reference to it in a peer-reviewed publication. A team of scientists from … more »
Multi-omics maps of cotton fibre reveal epigenetic basis for staged single-cell differentiation
April 2016 Authors: Maojun Wang, Pengcheng Wang, Lili Tu, Sitao Zhu, Lin Zhang, Zhonghua Li, Qinghua Zhang, Daojun Yuan, and Xianlong Zhang Info: Scientists from Huazhong Agricultural University in China studied the epigenetics of single-cell differentiation in cotton, finding clear … more »