Tag Archives: NGS sample prep

In Nature Biotech Paper, ABRF Group Reports Cross-Platform RNA-seq Findings

Posted on September 17, 2014 by Alex

If there’s a group you can count on to do the detailed work of putting instruments through their paces to help scientists perform better science, it’s the Association of Biomolecular Resource Facilities. In a new Nature Biotechnology paper, the next-gen … more »

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From the Land of Sun to the Land that Sun Forgot

Posted on February 19, 2014 by Alex

It was with great reluctance that the Sage Science team boarded planes taking us back to snowy Boston after a sunny and productive AGBT meeting in Florida. One of the key messages of this year’s Marco Island conference was that … more »

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As Sequencing Techs Mature, Scientists Look to Sample Prep for Improvements

Posted on February 14, 2014 by Alex

We come to AGBT year after year because it is the place for new advances in DNA sequencing. But this year we’re hearing more and more about a cause that has special importance to us: sample prep. In the first … more »

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ChIP-Seq sample prep tip – Interpreting the apparent presence of a secondary band in size-selected DNA

Posted on June 14, 2011 by Alex

ChIP-Seq analysis is used to study the control of gene expression by identifying DNA regions that are associated  with chromatin at the time of cellular analysis. The ChIP-Seq procedure typically involves cross-linking DNA to the associated chromatin proteins, sonication to … more »

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