Single molecule counting and assessment of random molecular tagging errors with transposable giga-scale error-correcting barcodes

September 2017

Billy Lau and Hanlee Ji

Scientists aimed to address errors that occur with conventional molecular barcodes for RNA-seq workflows. They developed transposable error-correcting barcodes with tens of billions of unique labels and found that this approach mitigates such problems. They validated the approach in a project that incorporated Pippin Prep to remove PCR products smaller than 500 bp.

BMC Genomics 201718:745
doi: 10.1186/s12864-017-4141-4

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