Population genomics of intrapatient HIV-1 evolution

December 2015

Fabio Zanini, Johanna Brodin, Lina Thebo, Christa Lanz, Göran Bratt, Jan Albert, and Richard Neher

Researchers from Germany and Sweden sequenced several samples collected over time from each of nine patients with HIV-1 to assess genetic diversity and minor variants of the virus as it evolved. Sequencing was performed on an Illumina MiSeq, with size selection of the Nextera library conducted with BluePippin.

eLife 2015;4:e11282

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