Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution

February 2017

Gavin G. Rutledge, Ulrike Böhme, Mandy Sanders, Adam J. Reid, et al.

In this paper, scientists generated a new reference genome and a manually curated draft assembly for two Plasmodium species. This effort made it possible to resolve discrepancies in the Plasmodium phylogeny and indicates host-specific adaptations as the organism entered new species. Sequencing of P. malariae was performed on PacBio after size selection with BluePippin.

Nature 542, 101–104

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