Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution

February 2017

Authors:
Gavin G. Rutledge, Ulrike Böhme, Mandy Sanders, Adam J. Reid, et al.

Info:
In this paper, scientists generated a new reference genome and a manually curated draft assembly for two Plasmodium species. This effort made it possible to resolve discrepancies in the Plasmodium phylogeny and indicates host-specific adaptations as the organism entered new species. Sequencing of P. malariae was performed on PacBio after size selection with BluePippin.

Citation:
Nature 542, 101–104
doi:10.1038/nature21038

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