Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify

October 2017

Malgorzata Komor, Thang Pham, Annemieke Hiemstra, Sander Piersma, et al.

In this paper, scientists from the Netherlands Cancer Institute, VU University Medical Center, and other institutions describe results from a new pipeline to detect differentially expressed protein isoforms. The method uses RNA sequencing and tandem mass spectrometry. In validation studies, the team used SageELF to separate library fractions into several size bins.

Molecular & Cellular Proteomics 16,1850-1863

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