High-specificity detection of rare alleles with Paired-End Low Error Sequencing (PELE-Seq)

June 2016

Authors:
Jessica L. Preston, Ariel E. Royall, Melissa A. Randel, Kristin L. Sikkink, Patrick C. Phillips, and Eric A. Johnson

Info:
Scientists at the University of Oregon developed a new protocol to reduce sequencing and PCR errors, resulting in more accurate SNP detection even for rare variants. Pippin Prep was used for tight sizing of sequencing libraries prior to paired-end Illumina sequencing.

Citation
BMC Genomics 201617:464
DOI: 10.1186/s12864-016-2669-3

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