High-specificity detection of rare alleles with Paired-End Low Error Sequencing (PELE-Seq)

June 2016

Jessica L. Preston, Ariel E. Royall, Melissa A. Randel, Kristin L. Sikkink, Patrick C. Phillips, and Eric A. Johnson

Scientists at the University of Oregon developed a new protocol to reduce sequencing and PCR errors, resulting in more accurate SNP detection even for rare variants. Pippin Prep was used for tight sizing of sequencing libraries prior to paired-end Illumina sequencing.

BMC Genomics 201617:464
DOI: 10.1186/s12864-016-2669-3

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