EpiRADseq: scalable analysis of genomewide patterns of methylation using next-generation sequencing

August 2015

Drew R. Schield, Matthew R. Walsh, Daren C. Card, Audra L. Andrew, Richard H. Adams and Todd A. Castoe

University of Texas researchers present a new method for quantifying methylation patterns across whole genomes at low cost. EpiRADseq is based on the ddRAD-seq protocol and uses a restriction enzyme that’s sensitive to methylation. DNA sizing is performed with an automated Pippin system.

Methods in Ecology and Evolution
Volume 7, Issue 1, pages 60–69

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