CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription

December 2015

Zhonghui Tang, Oscar Junhong Luo, Xingwang Li, et al.

Scientists from the Jackson Lab and many collaborating institutes used the ChIA-PET strategy with other data sets to understand how genome organization affects transcription in human cells. They analyzed gene expression with the Iso-Seq method on a PacBio system, using SageELF for size selection.

Cell 163, 1611–1627
DOI: 10.1016/j.cell.2015.11.024

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