Production of the Bioactive Compounds Violacein and Indolmycin Is Conditional in a maeA Mutant of Pseudoalteromonas luteoviolaceaS4054 Lacking the Malic Enzyme

September 2016

Mariane S. Thøgersen, Marina W. Delpin, Jette Melchiorsen, Mogens Kilstrup, Maria Månsson, Boyke Bunk, Cathrin Spröer, Jörg Overmann, Kristian F. Nielsen, and Lone Gram

A team of scientists analyzed biological compounds produced by Pseudoalteromonas luteoviolacea, a marine bacterium. They determined that the compounds, suspected to have antibacterial activity, were not effective in that role and that the bacterium may be producing other undiscovered compounds that achieve this function. Sequencing was conducted with PacBio after size-selection with BluePippin for 10 kb libraries.

Front Microbiol. 2016; 7: 1461.
doi: 10.3389/fmicb.2016.01461

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