Oligomeric proanthocyanidins (OPCs) target cancer stem-like cells and suppress tumor organoid formation in colorectal cancer

February 2018


Shusuke Toden, Preethi Ravindranathan, Jinghua Gu, Jacob Cardenas, Madelaine Yuchang &
Ajay Goel

Scientists from Baylor University Medical Center studied the chemoprotective role of oligomeric proanthocyanidins, finding that they inhibited cellular proliferation and spurred apoptosis. RNA sequencing data showed that these elements disrupted self-renewal pathways. The team used PippinHT to size-select pooled libraries prior to RNA sequencing.

Scientific Reports
Vol 8, Article number: 3335(2018)

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