Detecting DNA cytosine methylation using nanopore sequencing

February 2017

Jared Simpson, Rachael Workman, PC Zuzarte, Matei David, LJ Dursi & Winston Timp

In this paper, scientists report developing algorithms to distinguish methylated from unmethylated DNA using the Oxford Nanopore MinION sequencer. They evaluated its performance by sequencing a human methylome. BluePippin was used to size-select libraries for 3,500 bp to 6,000 bp.

Nature Methods 14, 407–410 (2017)

This entry was posted in Citation and tagged , , . Bookmark the permalink.

Comments are closed.