A SINE insertion in ATP1B2 in Belgian Shepherd dogs affected by spongy degeneration with cerebellar ataxia (SDCA2)

August 2017

Authors:
Nico Mauri, Miriam Kleiter, Elisabeth Dietschi, Michael Leschnik, et al.

Info:
Scientists in Europe and the US studied the genetic basis for a neurodegenerative disorder in dogs. Through whole genome sequencing data, they found a SINE insertion in the ATP1B2 gene that appears to be causative for a subtype of the disorder. The team used PippinHT for size-selecting cDNA fragments prior to sequencing.

Citation:
G3: Genes, Genomes, Genetics

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