Category Archives: Blog

How to Work with Large DNA: Data from the Sage HLS Platform

The Sage Science R&D team has been hard at work on our newest tool, to be released later this year. The HLS platform, which we first described at the Festival of Genomics meeting in Boston last year, is our answer … more »

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Urban Mice: NYC Study Sheds Light on Population Diversity and Changes

They may make subway riders shudder, but New York City mice are the stars of a cool new paper outlining their evolutionary history during a rapid period of urbanization. Scientists from the City University of New York used ddRAD-seq to … more »

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Spotted in the Literature: The First PippinHT Publication!

We began shipping the high-throughput version of our automated Pippin DNA size selection platform last year, and it’s a thrill to see what we believe is the first reference to it in a peer-reviewed publication. A team of scientists from … more »

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Building on a RAD Idea

It’s been a few years since the Hoekstra lab at Harvard first published its double-digest RAD-seq protocol. Since then, the approach has been rapidly adopted by the community for massively parallel genotyping, particularly of non-model organisms, and has been the … more »

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New Publications Ponder the Basics of Life and What Makes Us Human

Two recent papers published in Science are not only landmarks in their fields, but also feature our BluePippin automated DNA size selection platform. We’re honored to be included in these important publications. The first paper, “Design and synthesis of a … more »

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Kick Up Your Heels for DNA Day

It’s that time of year again — the time our kids look at us, shake their heads, and ask, “There’s a day to celebrate DNA? Seriously?” But for those of us in the industry, DNA Day is a big deal. … more »

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Scientists Report Method for Secure Communication Using DNA

It’s a study that would make John le Carré proud. DARPA-funded MIT scientists published results of a new method for encrypting messages in synthetic DNA for highly secure communication. It popped up on our radar because our BluePippin automated size … more »

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New hyRAD Method Expands Use of RAD-seq to Degraded Samples

Since RAD-seq was first developed, we’ve seen a number of new versions and approaches from an enthusiastic scientific community. The latest was recently published in PLoS One and demonstrates a RAD-based method suitable for analyzing degraded DNA, an essential step … more »

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AGBT in Review: Long-Range Data for Better Genome Insight

AGBT is behind us, which means the Sage Science team is officially back to the land of fleece and flannel. We had a great time at the conference and especially enjoyed seeing all the attendees making the most of our … more »

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AGBT: The All-Nighter Parties Haven’t Broken Us Yet

We may be a little bleary-eyed, but so far we’re surviving the Super Bowl of genomics, better known as AGBT. Last night we had a blast co-sponsoring a party out on the golf course with PacBio, and we’re glad so … more »

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