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Category Archives: Blog
From the Land of Sun to the Land that Sun Forgot
It was with great reluctance that the Sage Science team boarded planes taking us back to snowy Boston after a sunny and productive AGBT meeting in Florida. One of the key messages of this year’s Marco Island conference was that … more »
Posted in Blog
Tagged agbt, NGS sample prep, SageELF
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At AGBT, a Big Day for Blue!
Our BluePippin instrument got a little celebrity treatment at AGBT today. Several PacBio users who spoke during the plenary and evening sessions noted that BluePippin is an essential part of their SMRT Sequencing pipeline. We were especially flattered to get … more »
Posted in Blog
Tagged agbt, BluePippin, DNA Sequencing, DNA size selection, library creation, SageELF
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As Sequencing Techs Mature, Scientists Look to Sample Prep for Improvements
We come to AGBT year after year because it is the place for new advances in DNA sequencing. But this year we’re hearing more and more about a cause that has special importance to us: sample prep. In the first … more »
Posted in Blog
Tagged agbt, ChIP-Seq, DNA Sequencing, DNA sizing, NGS sample prep
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At Mount Sinai, Precise Sizing and SMRT Sequencing Yield Unprecedented Read Length
At the Icahn Institute for Genomics and Multiscale Biology at Mount Sinai in New York City, scientists use automated DNA sizing together with long-read sequencing to analyze clinical samples, conduct routine surveillance on microbes, and more. Technology development expert Robert … more »
Posted in Blog, Uncategorized
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If We Close Our Eyes, We Can Almost Hear the Sound of Surf
This winter has been especially brutal at Sage headquarters in Massachusetts — it is possible that we have never anticipated the Marco Island conference with quite this level of enthusiasm! Next week we and hundreds of other scientists will flock … more »
At NYU’s Center for Genomics and Systems Biology, Pippin Allows for More Precise DNA Size Selection
At NYU’s Center for Genomics and Systems Biology (CGSB), the genomics sequencing core facility (GenCore) runs both infectious disease and model organism sequencing projects through its Illumina and Ion Torrent pipelines. In both workflows, they find Pippin Prep to be … more »
Posted in Blog
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Happy Holidays from All of Us at Sage!
Here at Sage Science headquarters in Beverly, Mass., we’ve already got visions of sugarplums dancing in our heads — so what better time to look back on the past year? We are happy to report that 2013 was a great … more »
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At Boston University, Pippin Makes Quick Work of ChIP-seq Prep
At Boston University, the Galagan lab is trying to get a complete picture of Mycobacterium tuberculosis — in particular, how the organism’s regulatory network functions. By methodically performing ChIP-seq on each transcription factor in the microbe, the scientists are using … more »
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Sanger Reports Improved Prep Protocols for Illumina Sequencing
A new publication in Current Protocols in Human Genetics offers a thorough description of library preparation steps for sequencing with Illumina instruments. “Improved Protocols for Illumina Sequencing” comes from senior author Harold Swerdlow at the Wellcome Trust Sanger Institute and … more »
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PGM + Pippin: Recent Publications Highlight DNA Sizing for Ion Workflow
Several papers have come out recently showcasing the use of our Pippin Prep with the PGM from Ion Torrent. We’re offering a synopsis of three of them below as a good way to demonstrate how different users are taking advantage … more »
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