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Category Archives: Blog
Double Pippin for Optimized RAD-seq
Scientists in China and the UK recently published an open-access optimized protocol for RAD-seq in the Theoretical and Applied Genetics journal. The method is targeted at large studies of plants and enables users to specify sequence coverage parameters. From lead … more »
Podcast: Kari Stefansson on 20 Years of Human Genomics
Mendelspod has turned out another terrific podcast, this one with Kari Stefansson, and we’re proud to have sponsored the thought-provoking discussion. As most people in the field know, Stefansson earned his fame as founder of DeCode Genetics, which has spent … more »
Scientists Use Multiple Technologies to Produce High-Quality Chinese Genome Assembly
A newly reported genome assembly of a Chinese individual, generated by scientists in China and the US, used long-read PacBio sequencing, short-read Illumina data, and BioNano Genomics physical maps to achieve remarkably high accuracy and contiguity. Along the way, the … more »
Posted in Blog
Tagged BluePippin, PacBio
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New GIAB Publication Characterizes Seven Genomes with 12 Technologies
The Genome in a Bottle Consortium is on a roll — and if you haven’t checked out the latest paper in Scientific Data, you’re missing out. “Extensive sequencing of seven human genomes to characterize benchmark reference materials” comes from lead … more »
Posted in Blog
Tagged BluePippin
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NCSU Scientist Incorporates Genomics for Better Blueberry Resources
Hamid Ashrafi is working to breed higher-quality blueberries that are amenable to mechanical harvest, larger in size, tastier, and have a longer shelf life. As an assistant professor at North Carolina State University, Ashrafi is bringing genomic tools to a … more »
Posted in Blog
Tagged BluePippin, isoseq, PacBio, SageELF
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SageELF Offers Unique Advantages for Long-Range Sequencing and CNV Analysis
We released our SageELF instrument two years ago, and seeing how scientists have adopted it for various NGS pipelines has been a wonderful journey. If you haven’t noticed these great uses, we’ll get you up to speed with this quick … more »
The Conference Month: Prepping for PacBio, ASM, FoG
It’s June, and you know what that means: genomics conference season is back! The Sage team will be attending several events this month and we hope to see you at least once. We kick off next week with PacBio’s annual … more »
For PacBio’s Iso-Seq Method, Users Deploy SageELF or BluePippin Size Selection
More and more scientists are using their PacBio systems for transcriptome studies, generating full-length isoforms with the Iso-Seq method. The number of novel transcripts discovered and the implications for alternative splicing are a not-so-subtle reminder that we still have a … more »
How to Work with Large DNA: Data from the Sage HLS Platform
The Sage Science R&D team has been hard at work on our newest tool, to be released later this year. The HLS platform, which we first described at the Festival of Genomics meeting in Boston last year, is our answer … more »
Urban Mice: NYC Study Sheds Light on Population Diversity and Changes
They may make subway riders shudder, but New York City mice are the stars of a cool new paper outlining their evolutionary history during a rapid period of urbanization. Scientists from the City University of New York used ddRAD-seq to … more »
Posted in Blog
Tagged ddRADseq, genotyping, HiSeq, Illumina, Pippin Prep
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