Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn
September 2011
Authors:
Laura G. Reinholdt, Yueming Ding, Griffith T. Gilbert, Anne Czechanski, Jeffrey P. Solzak, Randall J. Roper, Mark T. Johnson, Leah Rae Donahue, Cathleen Lutz, Muriel T. Davisson
Info:
Illumina PE libraries were constructed and size selected at 400bp “tight” setting on Pippin Prep prior to enrichment PCR and hybridization capture for genomic region surrounding the Down syndrome locus in mouse, to identify rearrangements in a much-studied Down’s syndrome model strain.
Citation:
Mamm Genome (2011) 22:685–691
Posted in Citation
Tagged DNA Sequencing, Paired-end Sequencing, Pippin Prep, Pippin System
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